Evidence map›Paper›PMID 32787277›Full record

ArticleMolecular pharmaceutics2020

Pharmacokinetic Modeling of [

Lara García-Varela, Wejdan M Arif, David Vállez García, Takeharu Kakiuchi, Hiroyuki Ohba, Norihiro Harada, Tetsuro Tago, Philip H Elsinga, Hideo Tsukada, Nicola Antonio Colabufo and 5 more

Open access · hybridAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Molecular pharmaceutics, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
1.4field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 24 citations in OpenAlex.

  1. Article
  2. Designing a Small Molecule for PET Radiotracing: [Molecules (Basel, Switzerland) · 2025
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  3. Article
  4. Review
  5. Review
  6. Quantification of P-glycoprotein function at the human blood-brain barrier using [European journal of nuclear medicine and molecular imaging · 2023
    Article
  7. Review
  8. Comparative vulnerability of PET radioligands to partial inhibition of P-glycoprotein at the blood-brain barrier: A criterion of choice?Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism · 2022
    Article
  9. Review
  10. First clinical assessment of [Annals of nuclear medicine · 2021
    Article
  11. Molecular pharmaceutics · 2021
    Article
  12. A new approach to produce [EJNMMI radiopharmacy and chemistry · 2021
    Article
  13. Pharmacokinetic Modeling of (Molecular pharmaceutics · 2021
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors at 4 institutions in 4 countries.

Lara García-VarelaDepartment of Nuclear Medicine and Molecular Imaging, University of Groningen, University Medical Center Groningen, Hanzeplein 1, P.O. Box 30001, Groningen 9713 GZ, the Netherlands.ORCID 0000-0001-9803-4708
Wejdan M ArifDepartment of Nuclear Medicine and Molecular Imaging, University of Groningen, University Medical Center Groningen, Hanzeplein 1, P.O. Box 30001, Groningen 9713 GZ, the Netherlands.
David Vállez GarcíaDepartment of Nuclear Medicine and Molecular Imaging, University of Groningen, University Medical Center Groningen, Hanzeplein 1, P.O. Box 30001, Groningen 9713 GZ, the Netherlands.
Takeharu KakiuchiCentral Research Laboratory, Hamamatsu Photonics KK, 5000 Hirakuchi, Hamakita, Hamamatsu, Shizuoka 434-8601, Japan.
Hiroyuki OhbaCentral Research Laboratory, Hamamatsu Photonics KK, 5000 Hirakuchi, Hamakita, Hamamatsu, Shizuoka 434-8601, Japan.
Norihiro HaradaCentral Research Laboratory, Hamamatsu Photonics KK, 5000 Hirakuchi, Hamakita, Hamamatsu, Shizuoka 434-8601, Japan.
Tetsuro TagoResearch Team for Neuroimaging, Tokyo Metropolitan Institute of Gerontology, 35-2 Sakae-cho, Itabashi-ku, Tokyo 173-0015, Japan.
Philip H ElsingaDepartment of Nuclear Medicine and Molecular Imaging, University of Groningen, University Medical Center Groningen, Hanzeplein 1, P.O. Box 30001, Groningen 9713 GZ, the Netherlands.
Hideo TsukadaCentral Research Laboratory, Hamamatsu Photonics KK, 5000 Hirakuchi, Hamakita, Hamamatsu, Shizuoka 434-8601, Japan.
Nicola Antonio ColabufoDepartment of Pharmacy, University of Bari Aldo Moro, Bari 70121, Italy.ORCID 0000-0001-5639-7746
Rudi A J O DierckxDepartment of Nuclear Medicine and Molecular Imaging, University of Groningen, University Medical Center Groningen, Hanzeplein 1, P.O. Box 30001, Groningen 9713 GZ, the Netherlands.
Aren van WaardeDepartment of Nuclear Medicine and Molecular Imaging, University of Groningen, University Medical Center Groningen, Hanzeplein 1, P.O. Box 30001, Groningen 9713 GZ, the Netherlands.
Jun ToyoharaResearch Team for Neuroimaging, Tokyo Metropolitan Institute of Gerontology, 35-2 Sakae-cho, Itabashi-ku, Tokyo 173-0015, Japan.
Ronald BoellaardDepartment of Nuclear Medicine and Molecular Imaging, University of Groningen, University Medical Center Groningen, Hanzeplein 1, P.O. Box 30001, Groningen 9713 GZ, the Netherlands.
Gert LuurtsemaDepartment of Nuclear Medicine and Molecular Imaging, University of Groningen, University Medical Center Groningen, Hanzeplein 1, P.O. Box 30001, Groningen 9713 GZ, the Netherlands.
University Medical Center Groningen · NLHamamatsu Photonics (Japan) · JPTokyo Metropolitan Institute of Gerontology · JPUniversity of Bari Aldo Moro · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

[

Indexed as

AnimalsATP Binding Cassette Transporter, Subfamily B, Member 1Blood-Brain BarrierBrainFluorine RadioisotopesIsoquinolinesKineticsMacaca mulattaMalePositron-Emission TomographyPrimatesQuinolinesRadionuclide ImagingRadiopharmaceuticalsTetrahydronaphthalenesATP Binding Cassette Transporter, Subfamily B, Member 1Fluorine-18Fluorine RadioisotopesIsoquinolinesMC225 compoundQuinolinesRadiopharmaceuticalstariquidarTetrahydronaphthaleneskinetic evaluationPETP-gp inhibitionP-gp tracerrhesus macaque

Identifiers

PMID32787277
PMCPMC7482398
OpenAlexW3047020777

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.