Evidence map›Paper›PMID 32787100›Full record

ArticleJournal of medicinal chemistry2020

Pharmacological Characterization of Low-to-Moderate Affinity Opioid Receptor Agonists and Brain Imaging with

Julian Ott, Mona M Spilhaug, Simone Maschauer, Waqas Rafique, Jimmy E Jakobsson, Karoline Hartvig, Harald Hübner, Peter Gmeiner, Olaf Prante, Patrick J Riss

Open access · hybridAbstract read
In one paragraph

Article in Journal of medicinal chemistry, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.3field-weighted citation impact, top 46% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 5 citations in OpenAlex.

  1. Pharmacokinetic neuroimaging to study the dose-related brain kinetics and target engagement of buprenorphine in vivo.Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology · 2021
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 2 institutions in 2 countries.

Julian OttDepartment of Nuclear Medicine, Molecular Imaging and Radiochemistry, Translational Research Center, Friedrich Alexander University Erlangen-Nürnberg (FAU), Schwabachanlage 12, D-91054 Erlangen, Germany.
Mona M SpilhaugRealomics SRI, Kjemisk Institutt, Universitetet i Oslo, N-0376 Oslo, Norway.
Simone MaschauerDepartment of Nuclear Medicine, Molecular Imaging and Radiochemistry, Translational Research Center, Friedrich Alexander University Erlangen-Nürnberg (FAU), Schwabachanlage 12, D-91054 Erlangen, Germany.ORCID 0000-0002-6550-933X
Waqas RafiqueRealomics SRI, Kjemisk Institutt, Universitetet i Oslo, N-0376 Oslo, Norway.
Jimmy E JakobssonRealomics SRI, Kjemisk Institutt, Universitetet i Oslo, N-0376 Oslo, Norway.ORCID 0000-0002-5266-0591
Karoline HartvigRealomics SRI, Kjemisk Institutt, Universitetet i Oslo, N-0376 Oslo, Norway.
Harald HübnerDepartment of Chemistry and Pharmacy, Medicinal Chemistry, Emil Fischer Center, Friedrich Alexander University Erlangen-Nürnberg (FAU), Nikolaus-Fiebiger-Straße 10, D-91058 Erlangen, Germany.
Peter GmeinerDepartment of Chemistry and Pharmacy, Medicinal Chemistry, Emil Fischer Center, Friedrich Alexander University Erlangen-Nürnberg (FAU), Nikolaus-Fiebiger-Straße 10, D-91058 Erlangen, Germany.ORCID 0000-0002-4127-197X
Olaf PranteDepartment of Nuclear Medicine, Molecular Imaging and Radiochemistry, Translational Research Center, Friedrich Alexander University Erlangen-Nürnberg (FAU), Schwabachanlage 12, D-91054 Erlangen, Germany.ORCID 0000-0003-0247-3656
Patrick J RissRealomics SRI, Kjemisk Institutt, Universitetet i Oslo, N-0376 Oslo, Norway.ORCID 0000-0002-3887-7065
Friedrich-Alexander-Universität Erlangen-Nürnberg · DEUniversity of Oslo · NO

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The 3,4-dichloro-

Indexed as

Positron-Emission TomographyAnimalsAutoradiographyBenzamidesBrainFemaleFluorine RadioisotopesIsotope LabelingProtein BindingRatsRats, Sprague-DawleyReceptors, Opioid, mubenzamideBenzamidesFluorine-18Fluorine RadioisotopesReceptors, Opioid, mu

Identifiers

PMID32787100
PMCPMC7497404
OpenAlexW3046441413

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.