ArticleChemical reviews2020
Generation of Alkyl Radicals: From the Tyranny of Tin to the Photon Democracy.
Article in Chemical reviews, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 92 papers.
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Who cites it
92 citing papers in PubMed.
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- Biginelli dihydropyrimidines: a tunable class of alkyl radical precursors.Chemical science · 2026Article
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- Thianthrenium Salts in Photochemistry.Accounts of chemical research · 2026Article
- Stereoselective vicinal C(sp³)-C bond formation via metallaphotoredox 1,2-difunctionalization of internal alkenes.Nature communications · 2026Article
- Photoenzymatic CspProceedings of the National Academy of Sciences of the United States of America · 2026Article
- Photocatalytic generation of amidine carbon radicals for aminodihydroquinoline synthesis.Nature communications · 2025Article
- Photocatalytic Addition ofOrganic letters · 2025Article
- Bimolecular Homolytic Substitution (SACS central science · 2025Review
- Chiral heterogeneous photocatalysts for enantioselective synthesis: standing on the shoulders of organocatalysis.Chemical science · 2025Review
- Modular synthesis of CFNature communications · 2025Article
- Rapid Methylation of Aryl Bromides Using Air-Stable DABCO-Bis(Trimethylaluminum) via Nickel Metallaphotoredox Catalysis.Angewandte Chemie (International ed. in English) · 2025Article
32 more citing papers are in PubMed but not listed here.
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Authors and funding
2 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Alkyl radicals are key intermediates in organic synthesis. Their classic generation from alkyl halides has a severe drawback due to the employment of toxic tin hydrides to the point that "flight from the tyranny of tin" in radical processes was considered for a long time an unavoidable issue. This review summarizes the main alternative approaches for the generation of unstabilized alkyl radicals, using photons as traceless promoters. The recent development in photochemical and photocatalyzed processes enabled the discovery of a plethora of new alkyl radical precursors, opening the world of radical chemistry to a broader community, thus allowing a new era of photon democracy.
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