Evidence map›Paper›PMID 32786277›Full record

ArticleACS infectious diseases2020

Discovery of a Potent Picolinamide Antibacterial Active against

Enrico Speri, Jeshina Janardhanan, Cesar Masitas, Valerie A Schroeder, Elena Lastochkin, William R Wolter, Jed F Fisher, Shahriar Mobashery, Mayland Chang

Abstract read
In one paragraph

Article in ACS infectious diseases, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed.

  1. A spectroscopic andRSC advances · 2026
    Article
  2. Article
  3. Article
  4. A Potent and Narrow-Spectrum Antibacterial againstJournal of medicinal chemistry · 2023
    Article
  5. Article
  6. A dual-action antibiotic that killsProceedings of the National Academy of Sciences of the United States of America · 2023
    Article
  7. Article
  8. Review
  9. Unconventional Antibacterials and Adjuvants.Accounts of chemical research · 2021
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Enrico Speri
Jeshina Janardhanan
Cesar Masitas
Valerie A Schroeder
Elena Lastochkin
William R Wolter
Jed F Fisher
Shahriar MobasheryORCID 0000-0002-7695-7883

Funding

Inducible Antibiotic Resistance in Methicillin-Resistant Staphylococcus AureusR01AI104987 · NIAID · UNIVERSITY OF NOTRE DAME · PI Shahriar Mobashery · 2013 to 2026
$7.3M
The quinazolinone class of antibacterial agentsR01AI116548 · NIAID · UNIVERSITY OF NOTRE DAME · PI CHANG, MAYLAND F · 2015 to 2019
$3.0M
NIAID NIH HHS R01 AI104987NIAID NIH HHS R01 AI116548
6 · The paper itself

Abstract

A major challenge for chemotherapy of bacterial infections is perturbation of the intestinal microbiota.

Indexed as

Clostridioides difficileAnimalsAnti-Bacterial AgentsClostridioidesPicolinic AcidsVancomycinAnti-Bacterial AgentspicolinamidePicolinic AcidsVancomycinC. difficile mouse infectionClostridioides difficileminimum inhibitory concentrationpicolinamide

Identifiers

PMID32786277
PMCPMC7716698

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.