Evidence map›Paper›PMID 32786158›Full record

ArticleAllergy2021

Combined analysis of transcriptomic and genetic data for the identification of loci involved in glucocorticosteroid response in asthma.

Natalia Hernandez-Pacheco, Mario Gorenjak, Staša Jurgec, Almudena Corrales, Andrea Jorgensen, Leila Karimi, Susanne J Vijverberg, Vojko Berce, Maximilian Schieck, Marialbert Acosta-Herrera and 17 more

Open access · bronzeAbstract read
In one paragraph

Article in Allergy, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
1.6field-weighted citation impact, top 17% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 16 citations in OpenAlex.

  1. Pharmacogenetics of childhood uncontrolled asthma.Expert review of clinical immunology · 2025
    Review
  2. Article
  3. Review
  4. Asthma Exacerbations: The Genes Behind the Scenes.Journal of investigational allergology & clinical immunology · 2023
    Review
  5. Article
  6. Article
  7. Review
  8. Article
  9. Identification ofJournal of personalized medicine · 2021
    Article
  10. Genetic Determinants of Poor Response to Treatment in Severe Asthma.International journal of molecular sciences · 2021
    Review
  11. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

27 authors at 12 institutions in 7 countries.

Natalia Hernandez-PachecoResearch Unit, Hospital Universitario N.S. de Candelaria, Universidad de La Laguna, Santa Cruz de Tenerife, Spain.ORCID 0000-0002-6313-1847
Mario GorenjakCenter for Human Molecular Genetics and Pharmacogenomics, Faculty of Medicine, University of Maribor, Maribor, Slovenia.
Staša JurgecCenter for Human Molecular Genetics and Pharmacogenomics, Faculty of Medicine, University of Maribor, Maribor, Slovenia.
Almudena CorralesResearch Unit, Hospital Universitario N.S. de Candelaria, Universidad de La Laguna, Santa Cruz de Tenerife, Spain.
Andrea JorgensenDepartment of Biostatistics, University of Liverpool, Liverpool, UK.
Leila KarimiDepartment of Medical Informatics, Erasmus University Medical Center, Rotterdam, The Netherlands.ORCID 0000-0002-1746-3314
Susanne J VijverbergDepartment of Respiratory Medicine, Amsterdam UMC, University of Amsterdam, Amsterdam, The Netherlands.ORCID 0000-0002-4579-4081
Vojko BerceCenter for Human Molecular Genetics and Pharmacogenomics, Faculty of Medicine, University of Maribor, Maribor, Slovenia.
Maximilian SchieckDepartment of Pediatric Pneumology and Allergy, University Children's Hospital Regensburg (KUNO), Regensburg, Germany.
Marialbert Acosta-HerreraCellular Biology and Immunology, Institute of Parasitology and Biomedicine López-Neyra (IPBLN), Consejo Superior de Investigaciones Científicas (CSIC), Granada, Spain.
Martin KerickCellular Biology and Immunology, Institute of Parasitology and Biomedicine López-Neyra (IPBLN), Consejo Superior de Investigaciones Científicas (CSIC), Granada, Spain.
Lesly-Anne Samedy-BatesDepartment of Medicine, University of California, San Francisco, San Francisco, CA, USA.
Roger TavendalePopulation Pharmacogenetics Group, Biomedical Research Institute, Ninewells Hospital, Medical School, University of Dundee, Dundee, UK.
Jesús VillarCIBER de Enfermedades Respiratorias, Instituto de Salud Carlos III, Madrid, Spain.
Somnath MukhopadhyayPopulation Pharmacogenetics Group, Biomedical Research Institute, Ninewells Hospital, Medical School, University of Dundee, Dundee, UK.
Munir PirmohamedDepartment of Molecular and Clinical Pharmacology, Institute of Translational Medicine, University of Liverpool, Liverpool, UK.
Katia M C VerhammeDepartment of Medical Informatics, Erasmus University Medical Center, Rotterdam, The Netherlands.
Michael KabeschDepartment of Pediatric Pneumology and Allergy, University Children's Hospital Regensburg (KUNO), Regensburg, Germany.ORCID 0000-0003-0697-1871
Daniel B HawcuttDepartment of Women's and Children's Health, University of Liverpool, Liverpool, UK.
Steve TurnerChild Health, University of Aberdeen, Aberdeen, UK.ORCID 0000-0001-8393-5060
Colin N PalmerPopulation Pharmacogenetics Group, Biomedical Research Institute, Ninewells Hospital, Medical School, University of Dundee, Dundee, UK.
Esteban G BurchardDepartment of Medicine, University of California, San Francisco, San Francisco, CA, USA.
Anke H Maitland-van der ZeeDepartment of Respiratory Medicine, Amsterdam UMC, University of Amsterdam, Amsterdam, The Netherlands.ORCID 0000-0002-0414-3442
Carlos FloresResearch Unit, Hospital Universitario N.S. de Candelaria, Universidad de La Laguna, Santa Cruz de Tenerife, Spain.ORCID 0000-0001-5352-069X
Uroš PotočnikCenter for Human Molecular Genetics and Pharmacogenomics, Faculty of Medicine, University of Maribor, Maribor, Slovenia.
Maria Pino-YanesResearch Unit, Hospital Universitario N.S. de Candelaria, Universidad de La Laguna, Santa Cruz de Tenerife, Spain.ORCID 0000-0003-0332-437X
PiCA and SysPharmPedia consortia
Universidad de La Laguna · ESUniversity of Maribor · SIUniversity of Liverpool · GBConsejo Superior de Investigaciones Científicas · ESErasmus MC · NLUniversity Hospital Regensburg · DEUniversity of California, San Francisco · USUniversity of Dundee · GBUtrecht University · NLBrighton and Sussex Medical School · GBSt. Michael's Hospital · CAUniversity of Aberdeen · GB

Funding

The Airway Functional Genomics of Bronchodilator Drug Response in Minority Children with AsthmaR01HL117004 · NHLBI · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI AHITUV, NADAV, SEIBOLD, MAX A · 2013 to 2022
$9.3M
CLINICAL, PHARMACOLOGY, DRUG ACTION &PHARMACOKINETICST32GM007546 · NIGMS · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI Radojka Savic · 1985 to 2026
$8.9M
Gene-environments and Admixture in Latino Asthmatics (GALA 2)R01ES015794 · NIEHS · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI BURCHARD, ESTEBAN GONZALEZ · 2008 to 2012
$5.4M
National Heart, Lung, and Blood Institute of the National Institute of Health X01HL134589NHLBI NIH HHS R01 HL117004NIEHS NIH HHS R01 ES015794Wellcome TrustWellcome Trust Biomedical Resource 099177/Z/12/Z
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

AsthmaTranscriptomeGenome-Wide Association StudyHumansPolymorphism, Single Nucleotideasthma treatmentchildhood asthmaexacerbationsgenetic polymorphismpharmacogenomics

Identifiers

PMID32786158
PMCPMC7908891
OpenAlexW3048665684

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.