Evidence map›Paper›PMID 32786045›Full record

ReviewPhysiological reports2020

How best to interpret measures of levels of oxygen in tissues to make them effective clinical tools for care of patients with cancer and other oxygen-dependent pathologies.

Harold M Swartz, Ann Barry Flood, Philip E Schaner, Howard Halpern, Benjamin B Williams, Brian W Pogue, Bernard Gallez, Peter Vaupel

Open access · goldAbstract readReview
In one paragraph

Review in Physiological reports, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 43 papers.

0numbers the graph read from it
0cells of the map it votes in
43citing papers in PubMed
2.0field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

43 citing papers in PubMed, 59 citations in OpenAlex.

  1. Article
  2. Review
  3. Activity-based CORedox biology · 2026
    Article
  4. Review
  5. Article
  6. Erythroid precursors regulate local oxygen tension and repair outcomes in the bone marrow niche.Proceedings of the National Academy of Sciences of the United States of America · 2025
    Article
  7. Article
  8. Article
  9. Oxygen dynamics and delivery strategies to enhance beta cell replacement therapy.American journal of physiology. Cell physiology · 2025
    Review
  10. Article
  11. Article
  12. Article
  13. Article
  14. Article
  15. Article
  16. Article
  17. Article
  18. Reframing SpOFrontiers in physiology · 2025
    Review
  19. Article
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 5 institutions in 3 countries.

Harold M SwartzDepartment of Radiology, Dartmouth Medical School, Hanover, NH, USA.ORCID 0000-0001-6057-6587
Ann Barry FloodDepartment of Radiology, Dartmouth Medical School, Hanover, NH, USA.ORCID 0000-0002-4035-3084
Philip E SchanerDepartment of Medicine, Section of Radiation Oncology, Dartmouth-Hitchcock Medical Center, Lebanon, NH, USA.
Howard HalpernDepartment Radiation and Cellular Oncology, University of Chicago, Chicago, IL, USA.
Benjamin B WilliamsDepartment of Radiology, Dartmouth Medical School, Hanover, NH, USA.
Brian W PogueThayer School of Engineering, Dartmouth College, Hanover, NH, USA.
Bernard GallezLouvain Drug Research Institute, Université catholique de Louvain, Brussels, Belgium.
Peter VaupelDepartment Radiation Oncology, University Medical Center, University of Freiburg, Freiburg, Germany.
Dartmouth College · USDartmouth–Hitchcock Medical Center · USUCLouvain · BEUniversity of Chicago · USUniversity of Freiburg · DE

Funding

Translational Engineering in Cancer (TEC)P30CA023108 · NCI · DARTMOUTH COLLEGE · PI Fred W Kolling IV · 1985 to 2026
$91.3M
Very Low Frequency EPR Imaging in Vivo Phisiology P41 EB02034P41EB002034 · NIBIB · UNIVERSITY OF CHICAGO · PI HALPERN, HOWARD J · 2003 to 2017
$16.1M
Project 3: Direct & Repeated Measurement of pO2 in Deep-seated Tumors using EPR OP01CA190193 · NCI · DARTMOUTH COLLEGE · PI WILLIAMS, BENJAMIN B · 2015 to 2019
$7.0M
Radiation Biology of EPR Oxygen ImagesR01CA098575 · NCI · UNIVERSITY OF CHICAGO · PI HALPERN, HOWARD J · 2003 to 2022
$4.5M
NCI NIH HHS P01CA190193NCI NIH HHS P30 CA023108NCI NIH HHS R01 CA 098575NCI NIH HHS R01 CA098575NIBIB NIH HHS P41 002034
6 · The paper itself

Abstract

It is well understood that the level of molecular oxygen (O

Indexed as

Oxygen ConsumptionAnimalsHumansMagnetic Resonance ImagingNeoplasmsOptical ImagingOximetryOxygenOxygenclinical measures of oxygenoxygen in tissuespartial pressure

Identifiers

PMID32786045
PMCPMC7422807
OpenAlexW3048615952

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.