Evidence map›Paper›PMID 32785685›Full record

ArticleJournal of the National Cancer Institute2021

Temporal Trends in Opioid Prescribing Patterns Among Oncologists in the Medicare Population.

Vikram Jairam, Daniel X Yang, Saamir Pasha, Pamela R Soulos, Cary P Gross, James B Yu, Henry S Park

Open access · bronzeAbstract read
In one paragraph

Article in Journal of the National Cancer Institute, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 31 papers.

0numbers the graph read from it
0cells of the map it votes in
31citing papers in PubMed
4.9field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

31 citing papers in PubMed, 51 citations in OpenAlex.

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4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 1 country.

Vikram JairamDepartment of Therapeutic Radiology, Yale University School of Medicine, New Haven, CT, USA.
Daniel X YangDepartment of Therapeutic Radiology, Yale University School of Medicine, New Haven, CT, USA.
Saamir PashaCancer Outcomes, Public Policy, and Effectiveness Research (COPPER) Center, Yale University School, New Haven, CT, USA.
Pamela R SoulosCancer Outcomes, Public Policy, and Effectiveness Research (COPPER) Center, Yale University School, New Haven, CT, USA.
Cary P GrossCancer Outcomes, Public Policy, and Effectiveness Research (COPPER) Center, Yale University School, New Haven, CT, USA.
James B YuDepartment of Therapeutic Radiology, Yale University School of Medicine, New Haven, CT, USA.
Henry S ParkDepartment of Therapeutic Radiology, Yale University School of Medicine, New Haven, CT, USA.
Yale Cancer Center · USYale University · US

Funding

Yale Clinical and Translational Science Award (U Component)UL1TR001863 · NCATS · YALE UNIVERSITY · PI John H. Krystal, LUCILA OHNO-MACHADO · 2016 to 2026
$102.9M
NCATS NIH HHS UL1 TR001863
6 · The paper itself

Abstract

backgroundIn the wake of the US opioid epidemic, there have been efforts to curb opioid prescribing. However, it is unknown whether these efforts have affected prescribing among oncologists, whose patients often require opioids for symptom management. We investigated temporal patterns in opioid prescribing for Medicare beneficiaries among oncologists and nononcologists.

methodsWe queried the Centers for Medicare and Medicaid Services Part D prescriber dataset for all physicians between January 1, 2013, and December 31, 2017. We used population-averaged multivariable negative binomial regression to estimate the association between time and per-provider opioid and gabapentinoid prescribing rate, defined as the annual number of drug claims (original prescriptions and refills) per beneficiary, among oncologists and nononcologists on a national and state level.

resultsFrom 2013 to 2017, the national opioid-prescribing rate declined by 20.7% (P < .001) among oncologists and 22.8% (P < .001) among non oncologists. During this time frame, prescribing of gabapentin increased by 5.9% (P < .001) and 23.1% (P < .001) among oncologists and nononcologists, respectively. Among palliative care providers, opioid prescribe increased by 15.3% (P < .001). During the 5-year period, 43 states experienced a decrease (P < .05) in opioid prescribing among oncologists, and in 5 states, opioid prescribing decreased more among oncologists than nononcologists (P < .05).

conclusionsBetween 2013 and 2017, the opioid-prescribing rate statistically significantly decreased nationwide among oncologists and nononcologists, respectively. Given similar declines in opioid prescribing among oncologists and nononcologists, there is concern that opioid-prescribing guidelines intended for the noncancer population are being applied inappropriately to patients with cancer and cancer survivors.

Indexed as

Analgesics, OpioidCohort StudiesDrug PrescriptionsFemaleHumansMaleMedicareOncologistsPractice Patterns, Physicians'United StatesAnalgesics, Opioid

Identifiers

PMID32785685
PMCPMC7936059
OpenAlexW3063884216

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.