Evidence map›Paper›PMID 32785671›Full record

ArticleTransactions of the Royal Society of Tropical Medicine and Hygiene2020

Outcomes at 18 mo of 37 noma (cancrum oris) cases surgically treated at the Noma Children's Hospital, Sokoto, Nigeria.

Elise S Farley, Mohana Amirtharajah, Ryan D Winters, Abdurrazaq O Taiwo, Modupe J Oyemakinde, Adolphe Fotso, Linda A Torhee, Ushma C Mehta, Karla A Bil, Annick D Lenglet

Open access · hybridAbstract read
In one paragraph

Article in Transactions of the Royal Society of Tropical Medicine and Hygiene, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
1.6field-weighted citation impact, top 15% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 15 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Review
  5. Article
  6. Model of care, Noma Children's Hospital, northwest Nigeria.Tropical medicine & international health : TM & IH · 2021
    Article
  7. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 6 institutions in 4 countries.

Elise S FarleyMédecins Sans Frontières, Noma Children's Hospital, Sokoto, Nigeria.
Mohana AmirtharajahMédecins Sans Frontières, Amsterdam, the Netherlands.
Ryan D WintersDepartment of Otorhinolaryngology, Ochsner Health System, New Orleans, LA, USA.
Abdurrazaq O TaiwoDepartment of Dental and Maxillofacial Surgery, Usmanu Danfodiyo University Teaching Hospital, Sokoto, Nigeria.
Modupe J OyemakindeMédecins Sans Frontières, Noma Children's Hospital, Sokoto, Nigeria.
Adolphe FotsoMédecins Sans Frontières, Abuja, Nigeria.
Linda A TorheeMédecins Sans Frontières, Noma Children's Hospital, Sokoto, Nigeria.
Ushma C MehtaCentre for Infectious Disease Epidemiology and Research, School of Public Health and Family Medicine, University of Cape Town, South Africa.
Karla A BilMédecins Sans Frontières, Amsterdam, the Netherlands.
Annick D LengletMédecins Sans Frontières, Amsterdam, the Netherlands.
Médecins Sans Frontières · NLSokoto State University · NGUniversity of Cape Town · ZAOchsner Health System · USRadboud University Nijmegen · NLUsmanu Danfodiyo University Teaching Hospital, Sokoto · NG

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundNoma is a rapidly progressing infection of the oral cavity frequently resulting in severe facial disfigurement. We present a case series of noma patients surgically treated in northwest Nigeria.

methodsA retrospective analysis of routinely collected data (demographics, diagnosis and surgical procedures undergone) and in-person follow-up assessments (anthropometry, mouth opening and quality of life measurements) were conducted with patients who had surgery >6 mo prior to data collection.

resultsOf the 37 patients included, 21 (56.8%) were male and 22 (62.9%) were aged >6 y. The median number of months between last surgery and follow-up was 18 (IQR 13, 25) mo. At admission, the most severely affected anatomical area was the outer cheek (n = 9; 36.0% of patients had lost between 26% and 50%). The most frequent surgical procedures were the deltopectoral flap (n = 16; 43.2%) and trismus release (n = 12; 32.4%). For the eight trismus-release patients where mouth opening was documented at admission, all had a mouth opening of 0-20 mm at follow-up. All patients reported that the surgery had improved their quality of life.

conclusionsFollowing their last surgical intervention, noma patients do experience some improvements in their quality of life, but debilitating long-term sequelae persist.

Indexed as

NomaChildHospitalsHumansMaleNigeriaQuality of LifeRetrospective Studiescancrum orisnomaoutcomes

Identifiers

PMID32785671
PMCPMC7645286
OpenAlexW3053362950

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.