Evidence map›Paper›PMID 32785129›Full record

ArticleNutrients2020

Low Serum Vitamin B12 Levels Are Associated with Adverse Lipid Profiles in Apparently Healthy Young Saudi Women.

Sara Al-Musharaf, Ghadeer S Aljuraiban, Syed Danish Hussain, Abdullah M Alnaami, Ponnusamy Saravanan, Nasser Al-Daghri

Open access · goldAbstract read
In one paragraph

Article in Nutrients, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed
3.2field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

18 citing papers in PubMed, 33 citations in OpenAlex.

  1. Article
  2. Vitamin BThe Cochrane database of systematic reviews · 2026
    Article
  3. Article
  4. Article
  5. Article
  6. Vitamin BClinical nutrition ESPEN · 2025
    Observational
  7. Article
  8. Cardiovascular Nursing in Rehabilitative Cardiology: A Review.Journal of cardiovascular development and disease · 2025
    Review
  9. Article
  10. Article
  11. Article
  12. Review
  13. Article
  14. Article
  15. Deficiency of B vitamins leads to cholesterol-independent atherogenic transformation of the aorta.Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie · 2022
    Article
  16. Review
  17. Article
  18. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 2 countries.

Sara Al-MusharafDepartment of Community Health Sciences, College of Applied Medical Sciences, King Saud University, Riyadh 11451, Saudi Arabia.ORCID 0000-0002-7830-1415
Ghadeer S AljuraibanDepartment of Community Health Sciences, College of Applied Medical Sciences, King Saud University, Riyadh 11451, Saudi Arabia.ORCID 0000-0002-4866-5461
Syed Danish HussainChair for Biomarkers of Chronic Diseases, Riyadh Biochemistry Department, College of Science, King Saud University, Riyadh 11451, Saudi Arabia.
Abdullah M AlnaamiChair for Biomarkers of Chronic Diseases, Riyadh Biochemistry Department, College of Science, King Saud University, Riyadh 11451, Saudi Arabia.
Ponnusamy SaravananPopulation, Evidence and Technologies, Division of Health Sciences, Warwick Medical School, University of Warwick, Coventry CV2 2 DX, UK.ORCID 0000-0002-9566-2626
Nasser Al-DaghriChair for Biomarkers of Chronic Diseases, Riyadh Biochemistry Department, College of Science, King Saud University, Riyadh 11451, Saudi Arabia.
King Saud University · SAGeorge Eliot Hospital · GB

Funding

Medical Research Council MR/N006232/1Medical Research Council MR/R020981/1
6 · The paper itself

Abstract

An abnormal lipid profile is an independent risk factor for cardiovascular diseases. The relationship between vitamin B12 deficiency and lipid profile is inconclusive, with most studies conducted in unhealthy populations. In this study, we aimed to assess the relationship between serum vitamin B12 levels and lipid profiles in a cross-sectional study that included 341 apparently healthy Saudi women, aged 19-30 years, from different colleges at King Saud University, Saudi Arabia. Sociodemographic, anthropometric, biochemical, and lifestyle data were collected, including diet and physical activity. Serum vitamin B12 deficiency was defined as serum B12 level of <148 pmol/L. The prevalence of vitamin B12 deficiency was approximately 0.6%. Using multivariable linear regression models, serum vitamin B12 levels were found to be inversely associated with total cholesterol (B = -0.26;

Indexed as

Lipid MetabolismAdultAge FactorsBody Mass IndexCardiovascular DiseasesCross-Sectional StudiesFemaleHealthy VolunteersHumansObesityRisk FactorsSaudi ArabiaVitamin B 12Vitamin B 12 DeficiencyYoung AdultVitamin B 12healthylipid profileSaudi Arabiavitamin B12

Identifiers

PMID32785129
PMCPMC7468727
OpenAlexW3048085088

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.