Evidence map›Paper›PMID 32785125›Full record

ArticleInternational journal of molecular sciences2020

Structural Features of 1,3,4-Thiadiazole-Derived Ligands and Their Zn(II) and Cu(II) Complexes Which Demonstrate Synergistic Antibacterial Effects with Kanamycin.

Dariusz Karcz, Arkadiusz Matwijczuk, Daniel Kamiński, Bernadette Creaven, Ewa Ciszkowicz, Katarzyna Lecka-Szlachta, Karolina Starzak

Open access · goldAbstract read
In one paragraph

Article in International journal of molecular sciences, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed
3.2field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

18 citing papers in PubMed, 55 citations in OpenAlex.

  1. Antimicrobial Activity of 1,3,4-Thiadiazole Derivatives.Pharmaceuticals (Basel, Switzerland) · 2025
    Review
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  14. Design, Synthesis, and Evaluation of Novel 2Molecules (Basel, Switzerland) · 2022
    Article
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  16. The Physical Chemistry and Chemical Physics (PCCP) Section of theInternational journal of molecular sciences · 2021
    Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 5 institutions in 2 countries.

Dariusz KarczDepartment of Analytical Chemistry (C1), Faculty of Chemical Engineering and Technology, Cracow University of Technology, 31155 Kraków, Poland.ORCID 0000-0002-9848-2508
Arkadiusz MatwijczukDepartment of Biophysics, University of Life Sciences in Lublin, 20-950 Lublin, Poland.ORCID 0000-0003-2630-120X
Daniel KamińskiDepartment of General and Coordination Chemistry and Crystallography, Institute of Chemical Sciences, Maria Curie-Sklodowska University in Lublin, 20-031 Lublin, Poland.
Bernadette CreavenSchool of Chemical and Pharmaceutical Sciences, Technological University Dublin, Kevin St., D2 Dublin, Ireland.
Ewa CiszkowiczDepartment of Biotechnology and Bioinformatics, Faculty of Chemistry, Rzeszow University of Technology, 35-959 Rzeszów, Poland.ORCID 0000-0003-3401-2264
Katarzyna Lecka-SzlachtaDepartment of Biotechnology and Bioinformatics, Faculty of Chemistry, Rzeszow University of Technology, 35-959 Rzeszów, Poland.
Karolina StarzakDepartment of Analytical Chemistry (C1), Faculty of Chemical Engineering and Technology, Cracow University of Technology, 31155 Kraków, Poland.ORCID 0000-0002-0343-5363
Cracow University of Technology · PLRzeszów University of Technology · PLMaria Curie-Skłodowska University · PLTechnological University Dublin · IEUniversity of Life Sciences in Lublin · PL

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Classical synthetic protocols were applied for the isolation of three novel 1,3,4-thiadiazole derivatives which were then complexed with the biologically important Cu(II) and Zn(II) ions. All free ligands and their corresponding complexes were characterized using a number of spectroscopic techniques including Ultraviolet-visible (UV-vis), Fluorescence, Infrared (FT-IR), tandem liquid chromatography-mass (LC-MS), X-ray diffraction (XRD), and Nuclear Magnetic Resonance (NMR) spectroscopy (

Indexed as

Anti-Bacterial AgentsAntioxidantsChromatography, LiquidCoordination ComplexesCopperDrug SynergismKanamycinLigandsMagnetic Resonance SpectroscopyMass SpectrometryMicrobial Sensitivity TestsSpectroscopy, Fourier Transform InfraredStaphylococcus aureusThiadiazolesX-Ray DiffractionZinc1,3,4-thiadiazoleAnti-Bacterial AgentsAntioxidantsCoordination ComplexesCopperKanamycinLigandsThiadiazolesZinc1,3,4-thiadiazoleantibacterialantioxidantkanamycinneurodegenerationsynergistic effectthiadiazole complexthiadiazole ligands

Identifiers

PMID32785125
PMCPMC7461131
OpenAlexW3047716265

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.