Evidence map›Paper›PMID 32784939›Full record

ReviewNanomaterials (Basel, Switzerland)2020

The Potential of Silver Nanoparticles for Antiviral and Antibacterial Applications: A Mechanism of Action.

Atiqah Salleh, Ruth Naomi, Nike Dewi Utami, Abdul Wahab Mohammad, Ebrahim Mahmoudi, Norlaila Mustafa, Mh Busra Fauzi

Registry-linked trialAbstract readReview
In one paragraph

Review in Nanomaterials (Basel, Switzerland), 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT04894409 (Evaluation of Silver Nanoparticles as an Oropharyngeal Product), which is not on this map. Cited by 172 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
172citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT04894409 nacompletednot on this map

Evaluation of Silver Nanoparticles as an Oropharyngeal Product (Mouthwash) and Nasal Hygiene, by Health Personnel Working at the Tijuana General Hospital Exposed to Patients Diagnosed With Atypical Pneumonia Caused by SARS-CoV-2

TypeinterventionalSponsorCluster de Bioeconomia de Baja California, A.CRan2020 to 2020Enrolled231ConditionsCoronavirus Disease 2019 (COVID-19)ArmsMouthwash and nose rinse with the AgNPs solution, Mouthwashes and nose rinse in a conventional way
3 · Its place in the literature

Who cites it

172 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Trial
  3. Review
  4. Article
  5. Article
  6. A Novel Ag/AgCl/AgMicroorganisms · 2026
    Article
  7. Review
  8. Review
  9. Article
  10. Article
  11. Article
  12. Hydrothermally synthesized silver-decorated propolis quantum dots: a dual-action antibacterial and antioxidant nanocomposite.Photochemical & photobiological sciences : Official journal of the European Photochemistry Association and the European Society for Photobiology · 2026
    Article
  13. Article
  14. Review
  15. Review
  16. Article
  17. Article
  18. Review
  19. Article
  20. Article

112 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Atiqah SallehCentre for Tissue Engineering & Regenerative Medicine, Faculty of Medicine, Universiti Kebangsaan Malaysia, Kuala Lumpur 56000, Malaysia.ORCID 0000-0001-8344-7438
Ruth NaomiCentre for Tissue Engineering & Regenerative Medicine, Faculty of Medicine, Universiti Kebangsaan Malaysia, Kuala Lumpur 56000, Malaysia.ORCID 0000-0002-7937-1255
Nike Dewi UtamiCentre for Tissue Engineering & Regenerative Medicine, Faculty of Medicine, Universiti Kebangsaan Malaysia, Kuala Lumpur 56000, Malaysia.
Abdul Wahab MohammadDepartment of Chemical and Process Engineering, Faculty of Engineering and Built Environment, Universiti Kebangsaan Malaysia, Bangi 43600, Malaysia.
Ebrahim MahmoudiDepartment of Chemical and Process Engineering, Faculty of Engineering and Built Environment, Universiti Kebangsaan Malaysia, Bangi 43600, Malaysia.ORCID 0000-0002-1299-5063
Norlaila MustafaDepartment of Internal Medicine, Universiti Kebangsaan Malaysia Medical Centre (UKMMC), Kuala Lumpur 56000, Malaysia.ORCID 0000-0002-0196-7091
Mh Busra FauziCentre for Tissue Engineering & Regenerative Medicine, Faculty of Medicine, Universiti Kebangsaan Malaysia, Kuala Lumpur 56000, Malaysia.ORCID 0000-0001-6449-639X

Funding

Ministry of Education (Malaysia) Transdisciplinary Research Grant Scheme TRGS/1/2019/UKM/02/1/3
6 · The paper itself

Abstract

Rapid development of nanotechnology has been in high demand, especially for silver nanoparticles (AgNPs) since they have been proven to be useful in various fields such as medicine, textiles, and household appliances. AgNPs are very important because of their unique physicochemical and antimicrobial properties, with a myriad of activities that are applicable in various fields, including wound care management. This review aimed to elucidate the underlying mechanisms of AgNPs that are responsible for their antiviral properties and their antibacterial activity towards the microorganisms. AgNPs can be synthesized through three different methods-physical, chemical, and biological synthesis-as indicated in this review. The applications and limitations of the AgNPs such as their cytotoxicity towards humans and the environment, will be discussed. Based on the literature search obtained, the properties of AgNPs scrutinizing the antibacterial or antiviral effect shown different interaction towards bacteria which dependent on the synthesis processes followed by the morphological structure of AgNPs.

Indexed as

antimicrobialsantiviralcytotoxicitymechanism of actionnanotechnologysilver nanoparticles

Identifiers

PMID32784939
PMCPMC7466543

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.