ReviewInternational journal of molecular sciences2020
Cinnamic Acid Derivatives and Their Biological Efficacy.
Review in International journal of molecular sciences, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 185 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
185 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Global trends, translational gaps, and emerging research directions inFrontiers in fungal biology · 2026Pooled it
- Recent advancements in microtubule targeting agents for breast cancer: design strategies and pharmacological insights.Molecular diversity · 2026Review
- Integrated LC-Orbitrap-MS and network pharmacology decipher the pharmacological basis of Eucommiae folium in treating rheumatoid arthritis.Molecular diversity · 2026Article
- Mechanistic Insights into the Antibacterial Activity of Self-Assembled Nickel(II)-Triethanolamine-Cinnamate Complexes.ACS physical chemistry Au · 2026Article
- Design, Synthesis, and Cytotoxic Evaluation ofMolecules (Basel, Switzerland) · 2026Article
- Discovery of Novel Ligands for the Treatment of Cryptococcus neoformans Infection.Archiv der Pharmazie · 2026Article
- Comparative Evaluation of the Antioxidant Capacities of Commonly Consumed Dietary Polyphenols.Molecules (Basel, Switzerland) · 2026Article
- Comparative Study on Quantitative Analysis and In Vitro Antioxidant Potential of Leaf and Stem of Salvadora oleoides (Decne.) and Optimization of Flavonoids Using RSM.Biotechnology and applied biochemistry · 2026Article
- Cinnamic acid derivatives in agrochemicals: current use and future perspective.Journal of advanced research · 2026Review
- Phenolic Profiling of Some Bryophyte Species: In Vitro and In Silico Assessment of Their Antimicrobial Potentials.Molecules (Basel, Switzerland) · 2026Article
- Discovery of novel cinnamic acid derivatives with anti-Helicobacter pylori mechanism.Molecular diversity · 2026Article
- Review
- Histone demethylase CsJMJ12 enhances resistance of Navel orange to Penicillium digitatum via H3K27me3 demethylation.Journal of advanced research · 2026Article
- Anti-acne cinnamic acid bigel: a hybrid topical system for concurrent modulation of inflammation and microbial load.Inflammopharmacology · 2026Article
- Synthesis and Evaluation of Novel Cinnamic Acid Hybrids With Antiacetylcholinesterase, Antioxidant, and Anti-Inflammatory Properties.ChemMedChem · 2026Article
- Non-solvent cinnamic acid-based gel patch for transdermal drug delivery.Journal of advanced research · 2026Article
- Comprehensive glycoside identification and anti-inflammatory activity screening in Fructus Gardeniae and Fructus Gardeniae Grandiflorae.Food chemistry: X · 2026Article
- PLA Biocomposites Reinforced with Cinnamon-Treated Flax Fibers.Materials (Basel, Switzerland) · 2026Article
- Amelioration of acute liver failure by a cinnamic acid derivative through inhibition of the ROS-NETosis axis.Molecular biomedicine · 2026Article
- Anti-chikungunya Activity of a Cinnamic Acid Derivative: An In Vitro and In Silico Study.Molecular biotechnology · 2026Article
125 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors.
Funding
Abstract
The role played by cinnamic acid derivatives in treating cancer, bacterial infections, diabetes and neurological disorders, among many, has been reported. Cinnamic acid is obtained from cinnamon bark. Its structure is composed of a benzene ring, an alkene double bond and an acrylic acid functional group making it possible to modify the aforementioned functionalities with a variety of compounds resulting in bioactive agents with enhanced efficacy. The nature of the substituents incorporated into cinnamic acid has been found to play a huge role in either enhancing or decreasing the biological efficacy of the synthesized cinnamic acid derivatives. Some of the derivatives have been reported to be more effective when compared to the standard drugs used to treat chronic or infectious diseases in vitro, thus making them very promising therapeutic agents. Compound
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.