Evidence map›Paper›PMID 32784890›Full record

ReviewMolecules (Basel, Switzerland)2020

Natural Ingredient-Based Polymeric Nanoparticles for Cancer Treatment.

Ka Hong Wong, Aiping Lu, Xiaoyu Chen, Zhijun Yang

Abstract readReview
In one paragraph

Review in Molecules (Basel, Switzerland), 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 38 papers.

0numbers the graph read from it
0cells of the map it votes in
38citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

38 citing papers in PubMed.

  1. Review
  2. Review
  3. Review
  4. Review
  5. Chitosan-Nanomaterials (Basel, Switzerland) · 2025
    Article
  6. Review
  7. Review
  8. Review
  9. Review
  10. Review
  11. Review
  12. Article
  13. Article
  14. Review
  15. Article
  16. Review
  17. Knowledge-Based Design of Multifunctional Polymeric Nanoparticles.Handbook of experimental pharmacology · 2024
    Article
  18. Review
  19. Review
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Ka Hong WongSchool of Chinese Medicine, Hong Kong Baptist University, Hong Kong 999077, China.
Aiping LuSchool of Chinese Medicine, Hong Kong Baptist University, Hong Kong 999077, China.
Xiaoyu ChenSchool of Chinese Medicine, Hong Kong Baptist University, Hong Kong 999077, China.
Zhijun YangSchool of Chinese Medicine, Hong Kong Baptist University, Hong Kong 999077, China.ORCID 0000-0002-6094-0438

Funding

Hong Kong Baptist University Special Development Fund SDF18-0319-P03Innovation and Technology Commission - Hong Kong ITS/348/18FX
6 · The paper itself

Abstract

Cancer is a global health challenge. There are drawbacks to conventional chemotherapy such as poor bioavailability, development of drug resistance and severe side effects. Novel drug delivery system may be an alternative to optimize therapeutic effects. When such systems consist of natural materials, they offer important advantages: they are usually highly biocompatible, biodegradable, nontoxic and nonimmunogenic. Furthermore, natural materials can be easily modified for conjugation with a wide range of therapeutic agents and targeting ligands, according to the therapeutic purpose. This article reviews different natural ingredients and their applications in drug delivery systems for cancer therapy. Firstly, an overview of the polysaccharides and protein-based polymers that have been extensively investigated for drug delivery are described. Secondly, recent advances in using various natural ingredient-based polymeric nanoparticles for cancer therapy are reviewed. The characteristics of these delivery systems are summarized, followed by a discussion of future development and clinical potential. This review aims to summarize current knowledge and provide a basis for developing effective tailor-made formulations for cancer therapy in the future.

Indexed as

Drug Delivery SystemsAnimalsAntineoplastic AgentsBiocompatible MaterialsBiological ProductsDrug CarriersHumansNanoparticlesNeoplasmsPolymersAntineoplastic AgentsBiocompatible MaterialsBiological ProductsDrug CarriersPolymerscancer therapydrug delivery systemnanoparticlesnatural materialspolymers

Identifiers

PMID32784890
PMCPMC7463484

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.