Evidence map›Paper›PMID 32784649›Full record

ReviewInternational journal of molecular sciences2020

A Revolution toward Gene-Editing Technology and Its Application to Crop Improvement.

Sunny Ahmar, Sumbul Saeed, Muhammad Hafeez Ullah Khan, Shahid Ullah Khan, Freddy Mora-Poblete, Muhammad Kamran, Aroosha Faheem, Ambreen Maqsood, Muhammad Rauf, Saba Saleem and 2 more

Abstract readReview
In one paragraph

Review in International journal of molecular sciences, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 27 papers.

0numbers the graph read from it
0cells of the map it votes in
27citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

27 citing papers in PubMed.

  1. Advances in mutant characterization for detecting causal mutations in crop plants.TAG. Theoretical and applied genetics. Theoretische und angewandte Genetik · 2026
    Review
  2. Article
  3. Review
  4. Review
  5. Review
  6. Comparative analysis ofFrontiers in pharmacology · 2025
    Article
  7. Article
  8. Article
  9. Review
  10. Review
  11. Genome Editing and Protein Energy Malnutrition.Advances in experimental medicine and biology · 2023
    Article
  12. CRISPR-Based Genome Editing and Its Applications in Woody Plants.International journal of molecular sciences · 2022
    Review
  13. Review
  14. Review
  15. Review
  16. Review
  17. Article
  18. Review
  19. Review
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Sunny AhmarCollege of Plant Sciences and Technology Huazhong Agricultural University, Wuhan 430070, China.
Sumbul SaeedCollege of Plant Sciences and Technology Huazhong Agricultural University, Wuhan 430070, China.
Muhammad Hafeez Ullah KhanCollege of Plant Sciences and Technology Huazhong Agricultural University, Wuhan 430070, China.ORCID 0000-0001-8906-8033
Shahid Ullah KhanCollege of Plant Sciences and Technology Huazhong Agricultural University, Wuhan 430070, China.ORCID 0000-0002-3082-6079
Freddy Mora-PobleteInstitute of Biological Sciences, University of Talca, 2 Norte 685, Talca 3460000, Chile.ORCID 0000-0003-1428-0456
Muhammad KamranKey Laboratory of Arable Land Conservation (Middle and Lower Reaches of Yangtze River), Ministry of Agriculture, College of Resources and Environment, Huazhong Agricultural University, Wuhan 430070, China.ORCID 0000-0003-0781-0332
Aroosha FaheemSate Key Laboratory of Agricultural Microbiology and State Key Laboratory of Microbial Biosensor, College of Life Sciences Huazhong Agriculture University Wuhan, Wuhan 430070, China.
Ambreen MaqsoodDepartment of Plant Pathology, University College of Agriculture and Environmental Sciences, The Islamia University of Bahawalpur, Bahawalpur 63100, Pakistan.ORCID 0000-0002-0788-8909
Muhammad RaufNational Institute for Biotechnology and Genetic Engineering (NIBGE), Faisalabad 38000, Pakistan.ORCID 0000-0001-6713-5813
Saba SaleemDepartment of Bioscience, COMSATS Institute of Information Technology, Islamabad 45550, Pakistan.
Woo-Jong HongGraduate School of Biotechnology & Crop Biotech Institute, Kyung Hee University, Yongin 17104, Korea.ORCID 0000-0001-7240-6171
Ki-Hong JungGraduate School of Biotechnology & Crop Biotech Institute, Kyung Hee University, Yongin 17104, Korea.ORCID 0000-0003-0427-5901

Funding

Rural Development Administration PJ01325901Rural Development Administration PJ01366401Rural Development Administration PJ01492703
6 · The paper itself

Abstract

Genome editing is a relevant, versatile, and preferred tool for crop improvement, as well as for functional genomics. In this review, we summarize the advances in gene-editing techniques, such as zinc-finger nucleases (ZFNs), transcription activator-like (TAL) effector nucleases (TALENs), and clustered regularly interspaced short palindromic repeats (CRISPR) associated with the Cas9 and Cpf1 proteins. These tools support great opportunities for the future development of plant science and rapid remodeling of crops. Furthermore, we discuss the brief history of each tool and provide their comparison and different applications. Among the various genome-editing tools, CRISPR has become the most popular; hence, it is discussed in the greatest detail. CRISPR has helped clarify the genomic structure and its role in plants: For example, the transcriptional control of Cas9 and Cpf1, genetic locus monitoring, the mechanism and control of promoter activity, and the alteration and detection of epigenetic behavior between single-nucleotide polymorphisms (SNPs) investigated based on genetic traits and related genome-wide studies. The present review describes how CRISPR/Cas9 systems can play a valuable role in the characterization of the genomic rearrangement and plant gene functions, as well as the improvement of the important traits of field crops with the greatest precision. In addition, the speed editing strategy of gene-family members was introduced to accelerate the applications of gene-editing systems to crop improvement. For this, the CRISPR technology has a valuable advantage that particularly holds the scientist's mind, as it allows genome editing in multiple biological systems.

Indexed as

CRISPR-Cas SystemsCrops, AgriculturalEndonucleasesGene EditingGenome, PlantPlant BreedingEndonucleasesCRISPR/Cas9CRISPR/Cpf1crop improvementgenome editingspeed editing strategyTALEN

Identifiers

PMID32784649
PMCPMC7461041

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.