Evidence map›Paper›PMID 32784623›Full record

ArticleInternational journal of environmental research and public health2020

A Pilot Study to Assess Inhalation Exposures among Sugarcane Workers in Guatemala: Implications for Chronic Kidney Disease of Unknown Origin.

Joshua W Schaeffer, John L Adgate, Stephen J Reynolds, Jaime Butler-Dawson, Lyndsay Krisher, Miranda Dally, Richard J Johnson, Katherine A James, Diana Jaramillo, Lee S Newman

Open access · goldAbstract read
In one paragraph

Article in International journal of environmental research and public health, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.

0numbers the graph read from it
0cells of the map it votes in
19citing papers in PubMed
2.2field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

19 citing papers in PubMed, 35 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Article
  6. Heat-induced kidney disease: Understanding the impact.Journal of internal medicine · 2025
    Review
  7. Article
  8. Review
  9. Article
  10. Review
  11. American journal of physiology. Renal physiology · 2024
    Article
  12. Article
  13. Article
  14. Article
  15. Article
  16. Inhaled silica nanoparticles cause chronic kidney disease in rats.American journal of physiology. Renal physiology · 2022
    Article
  17. Review
  18. Article
  19. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 2 institutions in 1 country.

Joshua W SchaefferDepartment of Environmental and Occupational Health, Colorado School of Public Health, University of Colorado, Aurora, CO 80045, USA.
John L AdgateDepartment of Environmental and Occupational Health, Colorado School of Public Health, University of Colorado, Aurora, CO 80045, USA.ORCID 0000-0003-1271-3465
Stephen J ReynoldsDepartment of Environmental and Occupational Health, Colorado School of Public Health, University of Colorado, Aurora, CO 80045, USA.
Jaime Butler-DawsonDepartment of Environmental and Occupational Health, Colorado School of Public Health, University of Colorado, Aurora, CO 80045, USA.ORCID 0000-0002-1325-6246
Lyndsay KrisherDepartment of Environmental and Occupational Health, Colorado School of Public Health, University of Colorado, Aurora, CO 80045, USA.ORCID 0000-0001-7142-380X
Miranda DallyDepartment of Environmental and Occupational Health, Colorado School of Public Health, University of Colorado, Aurora, CO 80045, USA.ORCID 0000-0003-1537-3355
Richard J JohnsonDivision of Renal Diseases and Hypertension, Department of Medicine, School of Medicine, University of Colorado, Aurora, CO 80045, USA.
Katherine A JamesDepartment of Environmental and Occupational Health, Colorado School of Public Health, University of Colorado, Aurora, CO 80045, USA.ORCID 0000-0001-5119-398X
Diana JaramilloCenter for Health, Work and Environment, Colorado School of Public Health, University of Colorado, Aurora, CO 80045, USA.
Lee S NewmanDepartment of Environmental and Occupational Health, Colorado School of Public Health, University of Colorado, Aurora, CO 80045, USA.
Colorado School of Public Health · USUniversity of Colorado Anschutz Medical Campus · US

Funding

Etiologic and Mechanistic Factors Underlying Chronic Kidney Disease in Guatemalan Sugarcane WorkersR21ES028826 · NIEHS · UNIVERSITY OF COLORADO DENVER · PI NEWMAN, LEE S · 2018 to 2019
$505k
NIEHS NIH HHS R21-ES028826 and supplement R21-ES028826-01
6 · The paper itself

Abstract

backgroundSugarcane workers in Central America experience a heavy burden of chronic kidney disease of unknown origin. We conducted a pilot study among worker proxies in Guatemala to characterize exposures to particulate matter, silica, heavy metals, and glyphosate, as well as to examine potential nephrotoxic exposures.

methodsAir, soil, and ash samples were collected and analyzed using scanning electron microscopy, X-ray diffraction, inductively coupled plasma mass spectrometry, and an enzyme-linked immunosorbent assay.

resultsThe average mass concentration for particulate matter (PM)

conclusionSugarcane workers are exposed to high concentrations of particulate matter. Future studies should investigate the potential role of silica, heavy metals, and agrochemicals in the etiology of chronic kidney disease in this population.

Indexed as

Environmental MonitoringSaccharumAgricultural Workers' DiseasesAir PollutantsGuatemalaHumansInhalation ExposureParticulate MatterPilot ProjectsRenal Insufficiency, ChronicAir PollutantsParticulate MatterCKDuexposureskidneyparticulate mattersilicasugarcane workers

Identifiers

PMID32784623
PMCPMC7459472
OpenAlexW3047754595

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.