ArticleAntibiotics (Basel, Switzerland)2020
Active Pulmonary Tuberculosis in Elderly Patients: A 2016-2019 Retrospective Analysis from an Italian Referral Hospital.
Article in Antibiotics (Basel, Switzerland), 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 52 papers, 1 of them a synthesis that pooled it.
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Who cites it
52 citing papers in PubMed, 1 synthesis or guideline pooled it, 67 citations in OpenAlex.
- The asymptomatic tuberculosis proportion among the elderly population: a systematic review and meta-analysis.BMC public health · 2024Pooled it
- Comorbidity profiles and their impact on treatment outcomes in elderly patients with pulmonary tuberculosis: a single-center retrospective cohort study.BMC infectious diseases · 2026Article
- Epidemiological Distribution Characteristics of Tuberculosis Among Older Adults in Chongqing (2020-2024): Spatial-Temporal Analysis.JMIR public health and surveillance · 2026Article
- Rural Residence and One-Person Households Are Associated with Diagnostic Delay in Pulmonary Tuberculosis in a Low-Incidence European Setting.Tropical medicine and infectious disease · 2026Article
- Temporal trends in tuberculosis incidence among the aging population in Southwest China: a retrospective study.BMC geriatrics · 2026Article
- Abnormal Liver Function at the Time of Tuberculosis Diagnosis in South India.Indian journal of community medicine : official publication of Indian Association of Preventive & Social Medicine · 2026Article
- Prevalence ofIJID regions · 2026Article
- Sociodemographic and Clinical Factors Associated with Tuberculosis Mortality in Hamadan Province, Iran.Journal of research in health sciences · 2025Article
- Trends and delays in pulmonary tuberculosis diagnosis among elderly patients (≥ 60 Years) in Southern China: a 13-year surveillance data analysis (2010-2022).BMC public health · 2025Article
- Article
- Social participation and exposure to tuberculosis education: a cross-sectional study of older (≥ 60 years) domestic migrants in China.BMC public health · 2025Article
- Trends and impact of government prevention policies on pulmonary tuberculosis notification and mortality in Ningbo, China (2004-2021).Frontiers in tuberculosis · 2025Article
- Effect of population aging on pulmonary tuberculosis burden in Zhejiang Province, China: a population-based study.Frontiers in public health · 2025Article
- Predictors of treatment delay among drug resistant tuberculosis patients in Uganda.BMC infectious diseases · 2024Article
- Exploring anxiety in elderly pulmonary tuberculosis inpatients using propensity score matching method.BMC pulmonary medicine · 2024Article
- Analysis of the prevalence characteristics and risk factors of pulmonary tuberculosis combined with extrapulmonary tuberculosis in elderly patients.Scientific reports · 2024Article
- Survival Probability in Multidrug Resistant Pulmonary Tuberculosis Patients in a South Indian Region.Hospital pharmacy · 2024Article
- Elderly patients with tuberculosis in a low-incidence country - Clinical characteristics, inflammation and outcome.The Journal of infection · 2024Article
- High all-cause mortality and increasing proportion of older adults with tuberculosis in Texas, 2008-2020.Epidemiology and infection · 2024Article
- A Study on Risk Factors for Readmission of Elderly Patients with Pulmonary Tuberculosis Within One Month Using Propensity Score Matching Method.Infection and drug resistance · 2024Article
Corrections and comments
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Authors and funding
11 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Tuberculosis (TB) in the elderly (>65 years old) has increasingly become a global health problem. It has long been recognized that older people are vulnerable to developing tuberculosis. We retrospectively evaluated data from patients older than 65 years diagnosed with pulmonary TB admitted to the National Institute for Infectious Diseases L. Spallanzani, Rome, Italy, from 1 January 2016 to 31 December 2019. One hundred and six consecutive patients were diagnosed with pulmonary TB and 68% reported at least one comorbidity and 44% at least one of the TB risk-factors. Out of the 26 elderly patients who reported an adverse event, having risk factors for TB (O.R. (Odds Ratios) = 1.45; 95% CI 1.12-3.65) and the presence of cavities on Chest X-rays (O.R. = 1.42; 95% CI 1.08-2.73) resulted in being more likely to be associated with adverse events in elderly patients. Having weight loss (O.R. = 1.31; 95% CI 1.08-1.55) and dyspnea (O.R. = 1.23; 95% CI 1.13-1.41) resulted in being significant predictors of unsuccessful treatment outcome in elderly patients. Older people with TB represent a vulnerable group, with high mortality rate, with a challenging diagnosis. Hospitalizations in tertiary referral hospital with clinical expertise in TB management can be useful to improve the outcome of these fragile patients.
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