Evidence map›Paper›PMID 32784499›Full record

ReviewPharmaceuticals (Basel, Switzerland)2020

Emerging Therapeutic Modalities against COVID-19.

Shipra Malik, Anisha Gupta, Xiaobo Zhong, Theodore P Rasmussen, Jose E Manautou, Raman Bahal

Open access · goldAbstract readReview
In one paragraph

Review in Pharmaceuticals (Basel, Switzerland), 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
0.7field-weighted citation impact, top 18% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 26 citations in OpenAlex.

  1. Review
  2. Article
  3. Article
  4. Saudi pharmaceutical journal : SPJ : the official publication of the Saudi Pharmaceutical Society · 2022
    Review
  5. Article
  6. Article
  7. Article
  8. Review
  9. Article
  10. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Shipra MalikDepartment of Pharmaceutical Sciences, University of Connecticut, Storrs, CT 06269, USA.
Anisha GuptaDepartment of Chemistry, Wesleyan University, Middletown, CT 06459, USA.ORCID 0000-0002-0276-9169
Xiaobo ZhongDepartment of Pharmaceutical Sciences, University of Connecticut, Storrs, CT 06269, USA.ORCID 0000-0002-6537-5415
Theodore P RasmussenDepartment of Pharmaceutical Sciences, University of Connecticut, Storrs, CT 06269, USA.
Jose E ManautouDepartment of Pharmaceutical Sciences, University of Connecticut, Storrs, CT 06269, USA.
Raman BahalDepartment of Pharmaceutical Sciences, University of Connecticut, Storrs, CT 06269, USA.
University of Connecticut · USWesleyan University · US

Funding

NIH HHS 1R01CA241194-01A1NIH HHS 1R01HL147028-01A1
6 · The paper itself

Abstract

The novel SARS-CoV-2 virus has quickly spread worldwide, bringing the whole world as well as the economy to a standstill. As the world is struggling to minimize the transmission of this devastating disease, several strategies are being actively deployed to develop therapeutic interventions. Pharmaceutical companies and academic researchers are relentlessly working to investigate experimental, repurposed or FDA-approved drugs on a compassionate basis and novel biologics for SARS-CoV-2 prophylaxis and treatment. Presently, a tremendous surge of COVID-19 clinical trials are advancing through different stages. Among currently registered clinical efforts, ~86% are centered on testing small molecules or antibodies either alone or in combination with immunomodulators. The rest ~14% of clinical efforts are aimed at evaluating vaccines and convalescent plasma-based therapies to mitigate the disease's symptoms. This review provides a comprehensive overview of current therapeutic modalities being evaluated against SARS-CoV-2 virus in clinical trials.

Indexed as

antiviralcoronavirusCOVID-19remdesivirSARS-CoV-2vaccine

Identifiers

PMID32784499
PMCPMC7465781
OpenAlexW3048040891

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.