Evidence map›Paper›PMID 32784494›Full record

ArticleCancers2020

Identification and Validation of an

Lan Lan, Jiajun Liu, Minli Xing, Amber R Smith, Jinan Wang, Xiaoqing Wu, Carl Appelman, Ke Li, Anuradha Roy, Ragul Gowthaman and 8 more

Open access · goldAbstract read
In one paragraph

Article in Cancers, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed, 1 pooled it
1.3field-weighted citation impact, top 20% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 1 synthesis or guideline pooled it, 21 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Article
  4. Article
  5. Review
  6. Conversion of Polyethylenes into Fungal Secondary Metabolites.Angewandte Chemie (International ed. in English) · 2023
    Article
  7. Article
  8. Article
  9. [Advances in research of Musashi2 in solid tumors].Nan fang yi ke da xue xue bao = Journal of Southern Medical University · 2022
    Review
  10. Mechanism of RNA recognition by a Musashi RNA-binding protein.Current research in structural biology · 2022
    Review
  11. Review
  12. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

18 authors at 3 institutions in 1 country.

Lan LanDepartments of Molecular Biosciences, the University of Kansas, Lawrence, KS 66045, USA.ORCID 0000-0002-8045-7654
Jiajun LiuDepartments of Molecular Biosciences, the University of Kansas, Lawrence, KS 66045, USA.
Minli XingBio-NMR Core Facility, the University of Kansas, Lawrence, KS 66045, USA.
Amber R SmithDepartments of Molecular Biosciences, the University of Kansas, Lawrence, KS 66045, USA.
Jinan WangCenter for Computational Biology, the University of Kansas, Lawrence, KS 66045, USA.ORCID 0000-0003-0162-212X
Xiaoqing WuDepartments of Molecular Biosciences, the University of Kansas, Lawrence, KS 66045, USA.
Carl AppelmanDepartments of Molecular Biosciences, the University of Kansas, Lawrence, KS 66045, USA.
Ke LiDepartments of Molecular Biosciences, the University of Kansas, Lawrence, KS 66045, USA.
Anuradha RoyHigh Throughput Screening Laboratory, the University of Kansas, Lawrence, KS 66045, USA.
Ragul GowthamanCenter for Computational Biology, the University of Kansas, Lawrence, KS 66045, USA.
John KaranicolasProgram in Molecular Therapeutics, Fox Chase Cancer Center, Philadelphia, PA 19111, USA.ORCID 0000-0003-0300-726X
Amber D SomozaDepartment of Chemistry, University of Southern California, Los Angeles, CA 90007, USA.
Clay C C WangDepartment of Chemistry, University of Southern California, Los Angeles, CA 90007, USA.
Yinglong MiaoCenter for Computational Biology, the University of Kansas, Lawrence, KS 66045, USA.
Roberto De GuzmanDepartments of Molecular Biosciences, the University of Kansas, Lawrence, KS 66045, USA.
Berl R OakleyDepartments of Molecular Biosciences, the University of Kansas, Lawrence, KS 66045, USA.
Kristi L NeufeldDepartments of Molecular Biosciences, the University of Kansas, Lawrence, KS 66045, USA.ORCID 0000-0003-3653-9385
Liang XuDepartments of Molecular Biosciences, the University of Kansas, Lawrence, KS 66045, USA.ORCID 0000-0001-9196-4232
University of Kansas · USUniversity of Southern California · USFox Chase Cancer Center · US

Funding

Transgenic & Gene-Targeting Shared ResourceP30CA168524 · NCI · UNIVERSITY OF KANSAS MEDICAL CENTER · PI ROY A. JENSEN · 2012 to 2026
$40.1M
Synthetic Chemical Biology CoreP20GM113117 · NIGMS · UNIVERSITY OF KANSAS LAWRENCE · PI OROZCO, ROBIN C. · 2016 to 2025
$23.9M
U of Kansas/Haskell Indian Nations U.IRACDA ProjectK12GM063651 · NIGMS · UNIVERSITY OF KANSAS LAWRENCE · PI DE GUZMAN, ROBERTO N · 2002 to 2022
$10.0M
Molecular Genetic Mining of the Aspergillus Nidulans Secondary MetabolomeP01GM084077 · NIGMS · UNIVERSITY OF KANSAS LAWRENCE · PI OAKLEY, BERL RAY · 2008 to 2012
$5.4M
NMR studies of bacterial needle and tip proteinsR01AI074856 · NIAID · UNIVERSITY OF KANSAS LAWRENCE · PI DE GUZMAN, ROBERTO N · 2008 to 2018
$3.6M
THE MOLECULAR TARGET OF GAP JUNCTION ENHANCERSP30RR030926 · NCRR · UNIVERSITY OF KANSAS LAWRENCE · PI AUBE, JEFFREY · 2010 to 2011
$2.2M
Molecular cancer therapy targeting HuR-ARE interactionR01CA191785 · NCI · UNIVERSITY OF KANSAS LAWRENCE · PI AUBE, JEFFREY, XU, LIANG · 2015 to 2019
$2.1M
Small molecules modulating RNA-binding protein Msi1R01CA178831 · NCI · UNIVERSITY OF KANSAS LAWRENCE · PI NEUFELD, KRISTI L, XU, LIANG · 2014 to 2016
$1.3M
Kansas Bioscience Authority Rising Star AwardNational Institute of General Medical Science P01GM084077NCI NIH HHS P30 CA168524NCI NIH HHS R01 CA178831NCI NIH HHS R01 CA191785NCRR NIH HHS P30 RR030926NIAID NIH HHS R01 AI074856NIGMS NIH HHS K12 GM063651NIGMS NIH HHS P20 GM113117NIH HHS AI074856NIH HHS R01 CA178831NIH HHS R01 CA191785the University of Kansas Bold Aspiration Strategic Initiative Awardthe University of Kansas Endowment the Irving S. Johnson Fund
6 · The paper itself

Abstract

RNA-binding protein Musashi-1 (MSI1) is a key regulator of several stem cell populations. MSI1 is involved in tumor proliferation and maintenance, and it regulates target mRNAs at the translational level. The known mRNA targets of MSI1 include

Indexed as

cancer therapydrug discoveryfungi secondary metabolite derivativeMusashiNotch signalingRNA-binding proteinsWnt signaling

Identifiers

PMID32784494
PMCPMC7463734
OpenAlexW3047850251

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.