Evidence map›Paper›PMID 32784485›Full record

ArticleInternational journal of molecular sciences2020

Wnt/CTNNB1 Signal Transduction Pathway Inhibits the Expression of ZFP36 in Squamous Cell Carcinoma, by Inducing Transcriptional Repressors SNAI1, SLUG and TWIST.

Emma D Zanfi, Sebastian Fantini, Roberta Lotti, Matteo Bertesi, Alessandra Marconi, Alexis Grande, Rossella Manfredini, Carlo Pincelli, Tommaso Zanocco-Marani

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in International journal of molecular sciences, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
0.4field-weighted citation impact, top 40% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 6 citations in OpenAlex.

  1. Review
  2. Review
  3. Deregulation ofSaudi journal of biological sciences · 2024
    Article
  4. Wnt Signaling Pathways: From Inflammation to Non-Melanoma Skin Cancers.International journal of molecular sciences · 2023
    Review
  5. The mAnnals of translational medicine · 2022
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 1 institution in 1 country.

Emma D ZanfiLaboratory of Applied Biology, Department of Life Sciences, University of Modena and Reggio Emilia, 41125 Modena, Italy.ORCID 0000-0001-6633-9603
Sebastian FantiniCentre for Regenerative Medicine "Stefano Ferrari", Department of Life Sciences, University of Modena and Reggio Emilia, 41125 Modena, Italy.
Roberta LottiLaboratory of Cutaneous Biology, Department of Surgical, Medical, Dental and Morphological Sciences, University of Modena and Reggio Emilia, 41125 Modena, Italy.ORCID 0000-0003-2126-4147
Matteo BertesiLaboratory of Applied Biology, Department of Life Sciences, University of Modena and Reggio Emilia, 41125 Modena, Italy.
Alessandra MarconiLaboratory of Cutaneous Biology, Department of Surgical, Medical, Dental and Morphological Sciences, University of Modena and Reggio Emilia, 41125 Modena, Italy.
Alexis GrandeLaboratory of Applied Biology, Department of Life Sciences, University of Modena and Reggio Emilia, 41125 Modena, Italy.
Rossella ManfrediniCentre for Regenerative Medicine "Stefano Ferrari", Department of Life Sciences, University of Modena and Reggio Emilia, 41125 Modena, Italy.
Carlo PincelliLaboratory of Cutaneous Biology, Department of Surgical, Medical, Dental and Morphological Sciences, University of Modena and Reggio Emilia, 41125 Modena, Italy.
Tommaso Zanocco-MaraniLaboratory of Applied Biology, Department of Life Sciences, University of Modena and Reggio Emilia, 41125 Modena, Italy.ORCID 0000-0002-9911-7078
University of Modena and Reggio Emilia · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The Wnt/CTNNB1 pathway is often deregulated in epithelial tumors. The

Indexed as

Wnt Signaling PathwayBase SequenceCarcinoma, Squamous CellCell Line, TumorDown-RegulationGene Expression Regulation, NeoplasticGenome, HumanHumansKeratinocytesNuclear ProteinsPromoter Regions, GeneticRepressor ProteinsSnail Family Transcription FactorsSulfonamidesTristetraprolinTwist-Related Protein 1FH535Nuclear ProteinsRepressor ProteinsSNAI1 protein, humanSnail Family Transcription FactorsSulfonamidesTristetraprolinTWIST1 protein, humanTwist-Related Protein 1ZFP36 protein, humanEMTsquamous cell carcinomatranscriptional repressorsWnt/CTNNB1 signaling pathwayZFP36

Identifiers

PMID32784485
PMCPMC7461120
OpenAlexW3048270490

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.