ArticleThe Korean journal of internal medicine2020
Current findings of kidney biopsy including nephropathy associated with hypertension and diabetes mellitus in Korea.
Article in The Korean journal of internal medicine, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.
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14 citing papers in PubMed, 16 citations in OpenAlex.
- New strategy to regulate immunopathogenic processes of glomerulonephritis.Kidney research and clinical practice · 2026Article
- Clinical significance of renal histological diagnosis in patients with type 2 diabetes and proteinuria atypical for diabetic nephropathy.Journal of diabetes investigation · 2026Article
- A single-institution demographic study of pathologically proven kidney disease in South Korea over the last 33 years.Journal of pathology and translational medicine · 2025Article
- Kidney biopsy can help to predict renal outcomes of patients with type 2 diabetes mellitus.Kidney research and clinical practice · 2025Article
- Incidence rate of and risk factors for glomerulonephritis in patients with axial spondyloarthritis: a nationwide population-based study.Therapeutic advances in musculoskeletal disease · 2025Article
- Kidney Biopsy Findings Among Patients With Diabetes in the Cleveland Clinic Kidney Biopsy Epidemiology Project.Kidney medicine · 2024Article
- Article
- Distribution of pathological types and epidemiological characteristics based on kidney biopsy in Northwest China.Kidney research and clinical practice · 2023Article
- Comparison of dominant and nondominant C3 deposition in primary glomerulonephritis.Kidney research and clinical practice · 2023Article
- Glomerular filtration rate as a kidney outcome of diabetic kidney disease: a focus on new antidiabetic drugs.The Korean journal of internal medicine · 2022Review
- The role of inflammation in diabetic kidney disease.The Korean journal of internal medicine · 2021Review
- Blood pressure control in patients with chronic kidney disease.The Korean journal of internal medicine · 2021Review
- Changes in metabolic parameters and adverse kidney and cardiovascular events during glomerulonephritis and renal vasculitis treatment in patients with and without diabetes mellitus.Kidney research and clinical practice · 2021Article
- The Association between Serum Hemoglobin and Renal Prognosis of IgA Nephropathy.Journal of clinical medicine · 2021Article
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6 authors at 4 institutions in 1 country.
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Abstract
BACKGROUND/
aimsThis study aimed to investigate long-term temporal trends and outcomes of biopsy-proven kidney diseases in a multicenter kidney biopsy cohort, focusing on hypertension and diabetes, the leading causes of end-stage kidney disease (ESKD).
methodsThe study included a total of 21,426 patients who underwent kidney biopsy from 1979 to 2018 in 18 hospitals in Korea. We selected subgroups of adults with diabetes (n = 2,813) or clinically presumed hypertensive nephrosclerosis (HT-N, n = 2,917). Clinical, demographic, and laboratory data were collected in conjunction with pathologic findings. The prevalence of pathologically confirmed kidney diseases over time and their associations with clinical outcomes were evaluated.
resultsThe prevalence of biopsy-proven diabetic nephropathy (DN) has increased significantly from 2.5% to 6.0% in the total cohort in the recent 30 years with an increase in the prevalence of diabetes. Approximately 68% of total diabetic patients had non-diabetic renal disease (NDRD); the proportion was retained since 2000s. DN showed a significantly higher risk of ESKD than NDRD (hazard ratio [HR], 1.59; 95% confidence interval [CI], 1.35 to 1.88). The prevalence of biopsy-proven HT-N remained < 2% in the total cohort for several decades. There was no difference in risks of ESKD between patients with or without biopsy-proven HT-N (HR, 0.93; 95% CI, 0.54 to 1.59).
conclusionIn recent decades, the prevalence of diabetes and DN has significantly increased in the kidney biopsy cohort, showing an increased risk of ESKD. Despite the large numbers of patients meeting the clinical criteria of HT-N, most of those were diagnosed with pathologic diagnoses other than HT-N.
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