Evidence map›Paper›PMID 32784264›Full record

Observational studyBMJ open2020

Racial and ethnic disparities in SARS-CoV-2 pandemic: analysis of a COVID-19 observational registry for a diverse US metropolitan population.

Farhaan S Vahidy, Juan Carlos Nicolas, Jennifer R Meeks, Osman Khan, Alan Pan, Stephen L Jones, Faisal Masud, H Dirk Sostman, Robert Phillips, Julia D Andrieni and 2 more

Registry-linked trialOpen access · goldAbstract readObservational Study
In one paragraph

Observational study in BMJ open, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT04398264 (Characteristics of COVID-19 Infection Among PREGnant Women), which is not on this map. Cited by 172 papers, 9 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
172citing papers in PubMed, 9 pooled it
18.4field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT04398264 completednot on this map

Characteristics of COVID-19 Infection Among PREGnant Women

Typeobservational_patient_registrySponsorInova Health Care ServicesRan2020 to 2021Enrolled650ConditionsCorona Virus Infection, Pregnancy RelatedArmsCOVID-19 positive via testing
3 · Its place in the literature

Who cites it

172 citing papers in PubMed, 9 syntheses or guidelines pooled it, 263 citations in OpenAlex.

  1. Pooled it
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  3. Inequality in the distribution of Covid-19 vaccine: a systematic review.International journal for equity in health · 2022
    Pooled it
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  5. Update on SARS-CoV-2 seroprevalence: regional and worldwide.Clinical microbiology and infection : the official publication of the European Society of Clinical Microbiology and Infectious Diseases · 2021
    Pooled it
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  18. COVID-19 Readmission Is Highest Among Refugees in Denmark.International journal of environmental research and public health · 2025
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112 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 2 institutions in 1 country.

Farhaan S VahidyCenter for Outcomes Research, Houston Methodist Research Institute, Houston, Texas, USA fvahidy@houstonmethodist.org.ORCID 0000-0002-3464-2111
Juan Carlos NicolasCenter for Outcomes Research, Houston Methodist Research Institute, Houston, Texas, USA.
Jennifer R MeeksCenter for Outcomes Research, Houston Methodist Research Institute, Houston, Texas, USA.
Osman KhanCenter for Outcomes Research, Houston Methodist Research Institute, Houston, Texas, USA.
Alan PanCenter for Outcomes Research, Houston Methodist Research Institute, Houston, Texas, USA.
Stephen L JonesCenter for Outcomes Research, Houston Methodist Research Institute, Houston, Texas, USA.
Faisal MasudWeill Cornell Medicine, New York, New York, USA.
H Dirk SostmanWeill Cornell Medicine, New York, New York, USA.
Robert PhillipsCenter for Outcomes Research, Houston Methodist Research Institute, Houston, Texas, USA.
Julia D AndrieniWeill Cornell Medicine, New York, New York, USA.
Bita A KashCenter for Outcomes Research, Houston Methodist Research Institute, Houston, Texas, USA.
Khurram NasirCenter for Outcomes Research, Houston Methodist Research Institute, Houston, Texas, USA.
Houston Methodist · USCornell University · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionData on race and ethnic disparities for severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection are limited. We analysed sociodemographic factors associated with higher likelihood of SARS-CoV-2 infection and explore mediating pathways for race and ethnic disparities in the SARS-CoV-2 pandemic.

methodsThis is a cross-sectional analysis of the COVID-19 Surveillance and Outcomes Registry, which captures data for a large healthcare system, comprising one central tertiary care hospital, seven large community hospitals and an expansive ambulatory/emergency care network in the Greater Houston area. Nasopharyngeal samples for individuals inclusive of all ages, races, ethnicities and sex were tested for SARS-CoV-2. We analysed sociodemographic (age, sex, race, ethnicity, household income, residence population density) and comorbidity (Charlson Comorbidity Index, hypertension, diabetes, obesity) factors. Multivariable logistic regression models were fitted to provide adjusted OR (aOR) and 95% CI for likelihood of a positive SARS-CoV-2 test. Structural equation modelling (SEM) framework was used to explore three mediation pathways (low income, high population density, high comorbidity burden) for the association between non-Hispanic black (NHB) race, Hispanic ethnicity and SARS-CoV-2 infection.

resultsAmong 20 228 tested individuals, 1551 (7.7%) tested positive. The overall mean (SD) age was 51.1 (19.0) years, 62% were females, 22% were black and 18% were Hispanic. NHB and Hispanic ethnicity were associated with lower socioeconomic status and higher population density residence. In the fully adjusted model, NHB (vs non-Hispanic white; aOR, 2.23, CI 1.90 to 2.60) and Hispanic ethnicity (vs non-Hispanic; aOR, 1.95, CI 1.72 to 2.20) had a higher likelihood of infection. Older individuals and males were also at higher risk of infection. The SEM framework demonstrated a significant indirect effect of NHB and Hispanic ethnicity on SARS-CoV-2 infection mediated via a pathway including residence in densely populated zip code.

conclusionsThere is strong evidence of race and ethnic disparities in the SARS-CoV-2 pandemic that are potentially mediated through unique social determinants of health.

Indexed as

Health Status DisparitiesPandemicsRace FactorsAdultAgedBetacoronavirusBlack or African AmericanComorbidityCoronavirus InfectionsCOVID-19Cross-Sectional StudiesFemaleHispanic or LatinoHumansLogistic ModelsMaleepidemiologyinfectious diseasespublic health

Identifiers

PMID32784264
PMCPMC7418666
OpenAlexW3048785484

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.