Evidence map›Paper›PMID 32784239›Full record

ArticleBMJ case reports2020

Severe pre-eclampsia complicated by acute fatty liver disease of pregnancy, HELLP syndrome and acute kidney injury following SARS-CoV-2 infection.

Irshad Ahmed, Nashwa Eltaweel, Lina Antoun, Anoop Rehal

Open access · greenAbstract readCase Reports
In one paragraph

Article in BMJ case reports, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
20citing papers in PubMed, 3 pooled it
2.8field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

20 citing papers in PubMed, 3 syntheses or guidelines pooled it, 34 citations in OpenAlex.

  1. COVID-19 and Preeclampsia: A Systematic Review of Pathophysiological Interactions.Revista brasileira de ginecologia e obstetricia : revista da Federacao Brasileira das Sociedades de Ginecologia e Obstetricia · 2023
    Pooled it
  2. Pooled it
  3. Guideline
  4. COVID-19 related liver injuries in pregnancy.World journal of clinical cases · 2023
    Review
  5. Article
  6. Review
  7. Review
  8. Review
  9. Review
  10. Article
  11. Review
  12. Article
  13. Does COVID-19 cause pre-eclampsia?Ultrasound in obstetrics & gynecology : the official journal of the International Society of Ultrasound in Obstetrics and Gynecology · 2022
    Article
  14. COVID-19 and pregnancy: A comparison of case reports, case series and registry studies.European journal of obstetrics, gynecology, and reproductive biology · 2022
    Review
  15. Maternal and neonatal outcomes of pregnant patients with COVID-19: A prospective cohort study.International journal of gynaecology and obstetrics: the official organ of the International Federation of Gynaecology and Obstetrics · 2021
    Article
  16. Review
  17. Review
  18. Article
  19. Is COVID-19 a risk factor for severe preeclampsia? Hospital experience in a developing country.European journal of obstetrics, gynecology, and reproductive biology · 2021
    Article
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 1 country.

Irshad AhmedObstetrics and Gynaecology, University Hospitals Birmingham NHS Foundation Trust, Birmingham, UK irshad.ahmed@heartofengland.nhs.uk.
Nashwa EltaweelObstetrics and Gynaecology, Birmingham Heartlands Hospital, Birmingham, West Midlands, UK.
Lina AntounObstetrics and Gynaecology, Birmingham Heartlands Hospital, Birmingham, West Midlands, UK.
Anoop RehalObstetrics and Gynaecology, Birmingham Heartlands Hospital, Birmingham, West Midlands, UK.
Heartlands Hospital · GBUniversity Hospitals Birmingham NHS Foundation Trust · GB

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) pandemic has presented many diagnostic challenges and uncertainties. Little is known about common pathologies complicating pregnancy and how their behaviour is modified by the presence of SARS-CoV-2. Pregnancy itself can alter the body's response to viral infection, which can cause more severe symptoms. We report the first case of a patient affected with sudden-onset severe pre-eclampsia complicated by acute fatty liver disease of pregnancy, HELLP (haemolysis, elevated liver enzymes and low platelet) syndrome and acute kidney injury following SARS-CoV-2 infection. Although an initial diagnostic dilemma, a multidisciplinary team approach was required to ensure a favourable outcome for both the mother and the baby. Our case report highlights the need for health professionals caring for pregnant women to be aware of the complex interplay between SARS-CoV-2 infection and hypertensive disorders of pregnancy.

Indexed as

BetacoronavirusAcute Kidney InjuryAdultCoronavirus InfectionsCOVID-19Fatty LiverFemaleHELLP SyndromeHumansKidney Function TestsPandemicsPneumonia, ViralPre-EclampsiaPregnancyPregnancy ComplicationsPregnancy Complications, Infectioushaematology (incl blood transfusion)hypertensionliver diseaseobstetrics and gynaecologypregnancy

Identifiers

PMID32784239
PMCPMC7418688
OpenAlexW3048831463

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.