ArticlePediatrics2020
Community-Based Epidemiology of Hospitalized Acute Kidney Injury.
Article in Pediatrics, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.
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Who cites it
18 citing papers in PubMed.
- US Pediatric Hospitalizations Complicated by Acute Kidney Injury and Dialysis From 1997 to 2022.JAMA network open · 2026Article
- Using health systems evidence to study and predict long-term outcomes of childhood acute kidney injury.Pediatric nephrology (Berlin, Germany) · 2026Article
- The Challenges of AKI Determination in Children.Kidney international reports · 2026Article
- Optimization of Kidney Disease: Improving Global Outcomes Criteria for AKI for Pediatric Population.Kidney international reports · 2026Article
- Prenatal NSAIDs exposure and childhood kidney disease: a systematic review and meta-analysis.Frontiers in pediatrics · 2026Review
- Pediatric acute kidney injury is associated with impairment in nicotinamide adenine dinucleotide (NAD+) metabolism.Pediatric nephrology (Berlin, Germany) · 2025Observational
- Novel acute kidney injury biomarkers and their utility in children and adolescents-overview.Italian journal of pediatrics · 2025Review
- The challenges for developing prognostic prediction models for acute kidney injury in hospitalized children: A systematic review.Pediatric investigation · 2025Review
- The development and validation of a prediction model for post-AKI outcomes of pediatric inpatients.Clinical kidney journal · 2025Article
- Acute kidney injury in hospitalized children in 20 hospitals of China's Hunan Province: a cross-sectional survey.Renal failure · 2024Article
- Long-Term Kidney Outcomes after Pediatric Acute Kidney Injury.Journal of the American Society of Nephrology : JASN · 2024Article
- An update on the role of fluid overload in the prediction of outcome in acute kidney injury.Pediatric nephrology (Berlin, Germany) · 2024Review
- Incidence of Antimicrobial-Associated Acute Kidney Injury in Children: A Structured Review.Paediatric drugs · 2024Review
- Article
- Epidemiology of childhood acute kidney injury in England using e-alerts.Clinical kidney journal · 2023Article
- Renal arcuate vein thrombosis-induced acute kidney injury: a rare multiple-Hit-mediated disease.Clinical kidney journal · 2023Article
- Outcome prediction for acute kidney injury among hospitalized children via eXtreme Gradient Boosting algorithm.Scientific reports · 2022Article
- AKI in Hospitalized Children: Poorly Documented (and Underrecognized).Frontiers in pediatrics · 2021Article
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7 authors.
Funding
Abstract
backgroundAcute kidney injury (AKI) may lead to short- and long-term consequences in children, but its epidemiology has not been well described at a population level and outside of ICU settings.
methodsIn a large, diverse pediatric population receiving care within an integrated health care delivery system between 2008 and 2016, we calculated age- and sex-adjusted incidences of hospitalized AKI using consensus serum creatinine (SCr)-based diagnostic criteria. We also investigated the proportion of AKI detected in non-ICU settings and the rates of follow-up outpatient SCr testing after AKI hospitalization.
resultsAmong 1 500 546 children, the mean age was 9.8 years, 49.0% were female, and 33.1% were minorities. Age- and sex-adjusted incidence of hospitalized AKI among the entire pediatric population did not change significantly across the study period, averaging 0.70 (95% confidence interval: 0.68-0.73) cases per 1000 person-years. Among the subset of hospitalized children, the adjusted incidence of AKI increased from 6.0% of hospitalizations in 2008 to 8.8% in 2016. Approximately 66.7% of AKI episodes were not associated with an ICU stay, and 54.3% of confirmed, unresolved Stage 2 or 3 AKI episodes did not have outpatient follow-up SCr testing within 30 days postdischarge.
conclusionsCommunity-based pediatric AKI incidence was ∼1 per 1000 per year, with two-thirds of cases not associated with an ICU stay and more than one-half not receiving early outpatient follow-up kidney function testing. Further efforts are needed to increase the systematic recognition of AKI in all inpatient settings with appropriate, targeted postdischarge kidney function monitoring and associated management.
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