Evidence map›Paper›PMID 32784218›Full record

ArticleThe British journal of general practice : the journal of the Royal College of General Practitioners2020

Suboptimal prescribing behaviour associated with clinical software design features: a retrospective cohort study in English NHS primary care.

Brian MacKenna, Helen J Curtis, Alex J Walker, Seb Bacon, Richard Croker, Ben Goldacre

Abstract read
In one paragraph

Article in The British journal of general practice : the journal of the Royal College of General Practitioners, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed.

  1. Variation in duration of repeat prescriptions: a primary care cohort study in England.The British journal of general practice : the journal of the Royal College of General Practitioners · 2025
    Article
  2. Article
  3. Article
  4. Clinical coding of long COVID in English primary care: a federated analysis of 58 million patient recordsThe British journal of general practice : the journal of the Royal College of General Practitioners · 2021
    Article
  5. Article
  6. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Brian MacKennaThe DataLab, Nuffield Department of Primary Care Health Sciences, University of Oxford, Oxford.
Helen J CurtisThe DataLab, Nuffield Department of Primary Care Health Sciences, University of Oxford, Oxford.
Alex J WalkerThe DataLab, Nuffield Department of Primary Care Health Sciences, University of Oxford, Oxford.
Seb BaconThe DataLab, Nuffield Department of Primary Care Health Sciences, University of Oxford, Oxford.
Richard CrokerThe DataLab, Nuffield Department of Primary Care Health Sciences, University of Oxford, Oxford.
Ben GoldacreThe DataLab, Nuffield Department of Primary Care Health Sciences, University of Oxford, Oxford.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundElectronic health record (EHR) systems are used by clinicians to record patients' medical information, and support clinical activities such as prescribing. In England, healthcare professionals are advised to 'prescribe generically' because generic drugs are usually cheaper than branded alternatives, and have fixed reimbursement costs. 'Ghost-branded generics' are a new category of medicines savings, caused by prescribers specifying a manufacturer for a generic product, often resulting in a higher reimbursement price compared with the true generic.

aimTo describe time trends and practice factors associated with excess medication costs from ghost-branded generic prescribing. DESIGN AND

settingRetrospective cohort study of English GP prescribing data and EHR deployment data.

methodA retrospective cohort study was conducted, based on data from the OpenPrescribing.net database from May 2013 to May 2019. Total spending on ghost-branded generics across England was calculated, and excess spend on ghost-branded generics calculated as a percentage of all spending on generics for every CCG and general practice in England, for every month in the study period.

resultsThere were 31.8 million ghost-branded generic items and £9.5 million excess cost in 2018, compared with 7.45 million ghost-branded generic items and £1.3 million excess cost in 2014. Most excess costs were associated with one EHR, SystmOne, and it was identified that SystmOne offered ghost-branded generic options as the default. After informing the vendor, the authors monitored for subsequent change in costs, and report a rapid decrease in ghost-branded generic expenditure.

conclusionA design choice in a commonly used EHR has led to £9.5 million in avoidable excess prescribing costs for the NHS in 1 year. Notifying the vendor led to a change in user interface and a rapid, substantial spend reduction. This finding illustrates that EHR user interface design has a substantial impact on the quality, safety, and cost-effectiveness of clinical practice; this should be a priority for quantitative research.

Indexed as

Drugs, GenericState MedicineEnglandHumansPrimary Health CareRetrospective StudiesSoftware DesignDrugs, Genericclinical softwarecohort studiesdrugs prescribingghost-branded genericsprimary care

Identifiers

PMID32784218
PMCPMC7425205

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.