ArticleInternational journal of gynecological cancer : official journal of the International Gynecological Cancer Society2020
Exploring international differences in ovarian cancer treatment: a comparison of clinical practice guidelines and patterns of care.
Article in International journal of gynecological cancer : official journal of the International Gynecological Cancer Society, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers, 2 of them syntheses that pooled it.
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Who cites it
16 citing papers in PubMed, 2 syntheses or guidelines pooled it, 35 citations in OpenAlex.
- Guideline
- Ultra-radical (extensive) surgery versus standard surgery for the primary cytoreduction of advanced epithelial ovarian cancer.The Cochrane database of systematic reviews · 2022Pooled it
- Altered ANG/TIE gene expression in advanced ovarian cancer is not accompanied by disproportionate body water accumulation relative to perioperative fluid balance.Scientific reports · 2026Article
- Management of epithelial ovarian cancer in sub-Saharan Africa: a survey of practicing physicians.Ecancermedicalscience · 2026Article
- Worldwide barriers of optimal surgical care provision in advanced ovarian cancer.International journal of gynaecology and obstetrics: the official organ of the International Federation of Gynaecology and Obstetrics · 2025Review
- 'I was eager to do anything I could to improve the situation': a qualitative study of patients' experiences and views of prehabilitation for ovarian cancer surgery.BMC women's health · 2025Article
- Infrastructural and public health awareness gaps for the diagnosis and treatment of ovarian cancer: A literature review.Archives of gynecology and obstetrics · 2024Review
- Impact of Ovarian Cancer Surgery Volume on Overall and Progression-Free Survival: A Population-Based Retrospective National French Study.Annals of surgical oncology · 2024Article
- Exploring international differences in ovarian cancer care: a survey report on global patterns of care, current practices, and barriers.International journal of gynecological cancer : official journal of the International Gynecological Cancer Society · 2023Article
- Management of patients with advanced epithelial ovarian cancer: a European survey.Archives of gynecology and obstetrics · 2023Article
- Trends in survival for cancer patients aged 65 years or over from 1995 to 2014 in the United States: A population-based study.Cancer medicine · 2023Article
- Gynae-Oncology Surgeons' Preparedness to Undertake Colorectal Procedures during Cytoreductive Surgery for Ovarian Cancer: A Cross Sectional Survey.Journal of clinical medicine · 2022Article
- The Potential of Novel Lipid Agents for the Treatment of Chemotherapy-Resistant Human Epithelial Ovarian Cancer.Cancers · 2022Review
- Risk factors and prognostic implications of diagnosis of cancer within 30 days after an emergency hospital admission (emergency presentation): an International Cancer Benchmarking Partnership (ICBP) population-based study.The Lancet. Oncology · 2022Article
- Residual tumor and primary debulking surgery vs interval debulking surgery in stage IV epithelial ovarian cancer.Acta obstetricia et gynecologica Scandinavica · 2022Article
- Article
Corrections and comments
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Authors and funding
23 authors at 19 institutions in 10 countries.
Funding
Abstract
introductionThe International Cancer Benchmarking Partnership demonstrated international differences in ovarian cancer survival, particularly for women aged 65-74 with advanced disease. These findings suggest differences in treatment could be contributing to survival disparities.
objectiveTo compare clinical practice guidelines and patterns of care across seven high-income countries.
methodsA comparison of guidelines was performed and validated by a clinical working group. To explore clinical practice, a patterns of care survey was developed. A questionnaire regarding management and potential health system-related barriers to providing treatment was emailed to gynecological specialists. Guideline and survey results were crudely compared with 3-year survival by 'distant' stage using Spearman's rho.
resultsTwenty-seven guidelines were compared, and 119 clinicians completed the survey. Guideline-related measures varied between countries but did not correlate with survival internationally. Guidelines were consistent for surgical recommendations of either primary debulking surgery or neoadjuvant chemotherapy followed by interval debulking surgery with the aim of complete cytoreduction. Reported patterns of surgical care varied internationally, including for rates of primary versus interval debulking, extensive/'ultra-radical' surgery, and perceived barriers to optimal cytoreduction. Comparison showed that willingness to undertake extensive surgery correlated with survival across countries (r DISCUSSION: Findings suggest international variations in ovarian cancer treatment. Characteristics relating to countries with higher stage-specific survival included higher reported rates of primary surgery; willingness to undertake extensive/ultra-radical procedures; greater access to high-cost drugs; and auditing.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.