ReviewHearing research2020
The interplay of organ-of-Corti vibrational modes, not tectorial- membrane resonance, sets outer-hair-cell stereocilia phase to produce cochlear amplification.
Review in Hearing research, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.
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Who cites it
11 citing papers in PubMed, 17 citations in OpenAlex.
- Intracochlear overdrive: Characterizing nonlinear wave amplification in the mouse apex.The Journal of the Acoustical Society of America · 2023Article
- The Long Outer-Hair-Cell RC Time Constant: A Feature, Not a Bug, of the Mammalian Cochlea.Journal of the Association for Research in Otolaryngology : JARO · 2023Review
- Cochlear Amplification in the Short-Wave Region by Outer Hair Cells changing Organ-of-Corti area to Amplify the Fluid Traveling Wave.Hearing research · 2022Article
- Cochlear motion across the reticular lamina implies that it is not a stiff plate.Scientific reports · 2022Article
- Sound Induced Vibrations Deform the Organ of Corti Complex in the Low-Frequency Apical Region of the Gerbil Cochlea for Normal Hearing : Sound Induced Vibrations Deform the Organ of Corti Complex.Journal of the Association for Research in Otolaryngology : JARO · 2022Article
- Overturning the mechanisms of cochlear amplification via area deformations of the organ of Corti.The Journal of the Acoustical Society of America · 2022Article
- An outer hair cell-powered global hydromechanical mechanism for cochlear amplification.Hearing research · 2022Article
- Vector of motion measurements in the living cochlea using a 3D OCT vibrometry system.Biomedical optics express · 2022Article
- Cochlear Fluid Spaces and Structures of the Gerbil High-Frequency Region Measured Using Optical Coherence Tomography (OCT).Journal of the Association for Research in Otolaryngology : JARO · 2022Article
- Nonlinearity of intracochlear motion and local cochlear microphonic: Comparison between guinea pig and gerbil.Hearing research · 2021Article
- A role for tectorial membrane mechanics in activating the cochlear amplifier.Scientific reports · 2020Article
Corrections and comments
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Authors and funding
1 author at 1 institution in 1 country.
Funding
Abstract
The mechanical motions that deflect outer-hair-cell (OHC) stereocilia and the resulting effects of OHC motility are reviewed, concentrating on high-frequency cochlear regions. It has been proposed that a tectorial-membrane (TM) resonance makes the phase of OHC stereocilia motion be appropriate to produce cochlear amplification, i.e. so that the OHC force that pushes the basilar membrane (BM) is in the same direction as BM velocity. Evidence for and against the TM-resonance hypothesis are considered, including new cochlear-motion measurements using optical coherence tomography, and it is concluded that there is no such TM resonance. The evidence points to there being an advance in the phase of reticular lamina (RL) radial motion at a frequency approximately ½ octave below the BM characteristic frequency, and that this is the main source of the phase difference between the TM and RL radial motions that produces cochlear amplification. It appears that the change in phase of RL radial motion comes about because of a transition between different organ-of-Corti (OoC) vibrational modes that changes RL motion relative to BM and TM motion. The origins and consequences of the large phase change of RL radial motion relative to BM motion are considered; differences in the reported patterns of these changes may be due to different viewing angles. Detailed motion data and new models are needed to better specify the vibrational patterns of the OoC modes and the role of the various OoC structures in producing the modes and the mode transition.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.