Evidence map›Paper›PMID 32783799›Full record

Trial reportThe American journal of tropical medicine and hygiene2020

Baseline Characteristics of Study Participants in the Early Life Interventions for Childhood Growth and Development in Tanzania (ELICIT) Trial.

Tarina C Parpia, Sarah E Elwood, Rebecca J Scharf, Joann M McDermid, Anne W Wanjuhi, Elizabeth T Rogawski McQuade, Jean Gratz, Erling Svensen, Jonathan R Swann, Jeffrey R Donowitz and 8 more

Open access · bronzeAbstract readRandomized Controlled Trial
In one paragraph

Trial report in The American journal of tropical medicine and hygiene, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
0.7field-weighted citation impact, top 31% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 11 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

18 authors at 6 institutions in 4 countries.

Tarina C Parpia1Division of Infectious Diseases and International Health, University of Virginia, Charlottesville, Virginia.
Sarah E Elwood1Division of Infectious Diseases and International Health, University of Virginia, Charlottesville, Virginia.
Rebecca J Scharf2Department of Pediatrics, University of Virginia, Charlottesville, Virginia.
Joann M McDermid1Division of Infectious Diseases and International Health, University of Virginia, Charlottesville, Virginia.
Anne W Wanjuhi2Department of Pediatrics, University of Virginia, Charlottesville, Virginia.
Elizabeth T Rogawski McQuade1Division of Infectious Diseases and International Health, University of Virginia, Charlottesville, Virginia.
Jean Gratz1Division of Infectious Diseases and International Health, University of Virginia, Charlottesville, Virginia.
Erling Svensen3Haukeland University Hospital, Bergen, Norway.
Jonathan R Swann4School of Human Development and Health, Faculty of Medicine, University of Southampton, Southampton, United Kingdom.
Jeffrey R Donowitz5Division of Infectious Disease, Children's Hospital of Richmond at Virginia Commonwealth University, Richmond, Virginia.
Samwel Jatosh6Haydom Global Health Research Centre, Haydom Lutheran Hospital, Haydom, Tanzania.
Siphael Katengu6Haydom Global Health Research Centre, Haydom Lutheran Hospital, Haydom, Tanzania.
Paschal Mdoe6Haydom Global Health Research Centre, Haydom Lutheran Hospital, Haydom, Tanzania.
Sokoine Kivuyo7National Institute for Medical Research, Muhimbili Medical Research Centre, Dar es Salaam, Tanzania.
Eric R Houpt1Division of Infectious Diseases and International Health, University of Virginia, Charlottesville, Virginia.
Mark D DeBoer2Department of Pediatrics, University of Virginia, Charlottesville, Virginia.
Estomih Mduma6Haydom Global Health Research Centre, Haydom Lutheran Hospital, Haydom, Tanzania.
James A Platts-Mills1Division of Infectious Diseases and International Health, University of Virginia, Charlottesville, Virginia.
University of Virginia · USHaydom Lutheran Hospital · TZHaukeland University Hospital · NONational Institute for Medical Research · TZUniversity of Southampton · GBVirginia Commonwealth University · US

Funding

INFECTIOUS DISEASES TRAINING PROGRAMT32AI007046 · NIAID · UNIVERSITY OF VIRGINIA CHARLOTTESVILLE · PI Alison K Criss, William A Petri · 1985 to 2026
$15.3M
NIAID NIH HHS T32 AI007046
6 · The paper itself

Abstract

Recurrent enteric infections and micronutrient deficiencies, including deficiencies in the tryptophan-kynurenine-niacin pathway, have been associated with environmental enteric dysfunction, potentially contributing to poor child growth and development. We are conducting a randomized, placebo-controlled, 2 × 2 factorial interventional trial in a rural population in Haydom, Tanzania, to determine the effect of 1) antimicrobials (azithromycin and nitazoxanide) and/or 2) nicotinamide, a niacin vitamer, on attained length at 18 months. Mother/infant dyads were enrolled within 14 days of the infant's birth from September 2017 to September 2018, with the follow-up to be completed in February 2020. Here, we describe the baseline characteristics of the study cohort, risk factors for low enrollment weight, and neonatal adverse events (AEs). Risk factors for a low enrollment weight included being a firstborn child (-0.54 difference in weight-for-age

Indexed as

AdultAzithromycinBody WeightChild HealthChild Nutrition DisordersChild, PreschoolCohort StudiesEarly Medical InterventionFemaleHumansInfantInfant, NewbornMaleMothersNeonatal SepsisNiacinamideAzithromycinNiacinamidenitazoxanideNitro CompoundsThiazoles

Identifiers

PMID32783799
PMCPMC7543831
OpenAlexW3048401558

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.