Evidence map›Paper›PMID 32783650›Full record

ArticleJCO global oncology2020

Treatment and Outcomes of Colorectal Cancer in Armenia: A Real-World Experience From a Developing Country.

Samvel Bardakhchyan, Sergo Mkhitaryan, Davit Zohrabyan, Liana Safaryan, Armen Avagyan, Lilit Harutyunyan, Jemma Arakelyan, Gevorg Tamamyan, Armen Tananyan

Abstract read
In one paragraph

Article in JCO global oncology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Article
  2. Article
  3. Switching from messenger RNAs to noncoding RNAs,World journal of gastrointestinal oncology · 2025
    Review
  4. Article
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Samvel BardakhchyanDepartment of Oncology, Yerevan State Medical University, Yerevan, Armenia.
Sergo MkhitaryanBerd Military Hospital, Tavush, Armenia.
Davit ZohrabyanDepartment of Oncology, Yerevan State Medical University, Yerevan, Armenia.
Liana SafaryanDepartment of Oncology, Yerevan State Medical University, Yerevan, Armenia.
Armen AvagyanDepartment of Oncology, Yerevan State Medical University, Yerevan, Armenia.
Lilit HarutyunyanDepartment of Oncology, Yerevan State Medical University, Yerevan, Armenia.
Jemma ArakelyanDepartment of Oncology, Yerevan State Medical University, Yerevan, Armenia.
Gevorg TamamyanPediatric Cancer and Blood Disorders Center of Armenia, Hematology Center, Yerevan State Medical University, Yerevan, Armenia.
Armen TananyanDepartment of Oncology, Yerevan State Medical University, Yerevan, Armenia.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeIn Armenia, colorectal cancer (CRC) is one of the most frequently diagnosed cancers. It is in the third place by incidence. The aim of this study was to evaluate treatment and outcomes of CRC in Armenia during the last 9 years. MATERIALS AND

methodsFor this retrospective hospital-based study, we have collected data from two main oncology centers in Armenia: National Oncology Center and "Muratsan" Hospital of Yerevan State Medical University. The information about patients with CRC who were treated at these two centers between January 1, 2010 and July 1, 2018 was collected from the medical records. Log-rank test and Kaplan-Meier curves were used for survival analysis. Prognostic factors were identified by Cox regression.

resultsA total of 602 patients with CRC were involved in the final analysis. Median follow-up time was 37 months (range, 3-207 months). A total of 8.6% of patients had stage I, 32.9% stage II, 38.0% stage III, and 17.6% stage IV cancer; for 2.7% patients, the stage was unknown. The main independent prognostic factors for overall survival (OS) were tumor stage, grade, and histology. Adjuvant chemotherapy has been shown to improve survival in stage II colon cancer and stage III rectal but not in stage II rectal cancer. Radiotherapy did not yield survival improvement in stage II or III rectal cancer. Three- and 5-year OS rates were 62.9% and 51.8% for all stages combined and 79.7% and 68.5% for stages I-II, 62.5% and 48.4% for stage III, and 24.4% and 17% for stage IV respectively.

conclusionAs seen from our results, our survival rates are lower than those of the developed world. Additional research is needed to identify the underlying reasons and to improve patients' treatment and outcomes in Armenia.

Indexed as

Developing CountriesRectal NeoplasmsArmeniaHumansRetrospective StudiesTreatment Outcome

Identifiers

PMID32783650
PMCPMC7456313

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