Evidence map›Paper›PMID 32783608›Full record

ReviewPhysiology (Bethesda, Md.)2020

The SLC25 Carrier Family: Important Transport Proteins in Mitochondrial Physiology and Pathology.

Edmund R S Kunji, Martin S King, Jonathan J Ruprecht, Chancievan Thangaratnarajah

Open access · hybridAbstract readReview
In one paragraph

Review in Physiology (Bethesda, Md.), 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 129 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
129citing papers in PubMed, 1 pooled it
7.0field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

129 citing papers in PubMed, 1 synthesis or guideline pooled it, 169 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Review
  4. Article
  5. Article
  6. Review
  7. Article
  8. Article
  9. Article
  10. Article
  11. Decoding the Hot-Mitochondrion Paradox.BioEssays : news and reviews in molecular, cellular and developmental biology · 2026
    Review
  12. Review
  13. Article
  14. Article
  15. Review
  16. Article
  17. HNature chemical biology · 2026
    Article
  18. Article
  19. Article
  20. Article

69 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 2 countries.

Edmund R S KunjiMedical Research Council Mitochondrial Biology Unit, University of Cambridge, Cambridge, United Kingdom.ORCID 0000-0002-0610-4500
Martin S KingMedical Research Council Mitochondrial Biology Unit, University of Cambridge, Cambridge, United Kingdom.ORCID 0000-0001-6030-5154
Jonathan J RuprechtMedical Research Council Mitochondrial Biology Unit, University of Cambridge, Cambridge, United Kingdom.ORCID 0000-0002-1838-7245
Chancievan ThangaratnarajahGroningen Biomolecular Sciences and Biotechnology Institute, Membrane Enzymology, University of Groningen, Groningen, The Netherlands.ORCID 0000-0002-0279-6642
University of Cambridge · GBUniversity of Groningen · NL

Funding

Medical Research Council MC_UU_00015/1
6 · The paper itself

Abstract

Members of the mitochondrial carrier family (SLC25) transport a variety of compounds across the inner membrane of mitochondria. These transport steps provide building blocks for the cell and link the pathways of the mitochondrial matrix and cytosol. An increasing number of diseases and pathologies has been associated with their dysfunction. In this review, the molecular basis of these diseases is explained based on our current understanding of their transport mechanism.

Indexed as

Energy MetabolismAnimalsBiological TransportHumansMitochondriaMitochondrial DiseasesMitochondrial MembranesMitochondrial ProteinsMutation, MissenseOrganic Anion TransportersMitochondrial ProteinsOrganic Anion Transportersbioenergeticsimpaired transport mechanismmitochondrial diseasemitochondrial physiologypathological mutations

Identifiers

PMID32783608
PMCPMC7611780
OpenAlexW3048846827

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.