Evidence map›Paper›PMID 32783504›Full record

SynthesisTopics in stroke rehabilitation2021

Effectiveness of non-pharmacological interventions for treating post-stroke depressive symptoms: Systematic review and meta-analysis of randomized controlled trials.

Yejin Lee, Brian Chen, Mandy W M Fong, Jin-Moo Lee, Ginger E Nicol, Eric J Lenze, Lisa T Connor, Carolyn Baum, Alex W K Wong

Open access · greenAbstract readMeta-AnalysisSystematic Review
In one paragraph

Synthesis in Topics in stroke rehabilitation, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers, 4 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed, 4 pooled it
1.0field-weighted citation impact, top 22% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 4 syntheses or guidelines pooled it, 32 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Pooled it
  4. Pooled it
  5. Review
  6. Review
  7. Article
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  9. Article
  10. Article
  11. Review
  12. Evaluation & Treatment of Psychological Effects of Stroke.Delaware journal of public health · 2023
    Article
  13. Article
  14. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 1 institution in 1 country.

Yejin LeeProgram in Occupational Therapy, Washington University School of Medicine, St. Louis, MO, USA.ORCID 0000-0002-5140-9952
Brian ChenProgram in Occupational Therapy, Washington University School of Medicine, St. Louis, MO, USA.
Mandy W M FongDepartment of Neurology, Washington University School of Medicine, St. Louis, MO, USA.ORCID 0000-0002-8411-9214
Jin-Moo LeeDepartment of Neurology, Washington University School of Medicine, St. Louis, MO, USA.
Ginger E NicolDepartment of Psychiatry, Washington University School of Medicine, St. Louis, MO, USA.
Eric J LenzeDepartment of Psychiatry, Washington University School of Medicine, St. Louis, MO, USA.ORCID 0000-0002-0471-9368
Lisa T ConnorProgram in Occupational Therapy & Department of Neurology, Washington University School of Medicine, St. Louis, MO, USA.ORCID 0000-0002-9776-8328
Carolyn BaumProgram in Occupational Therapy & Department of Neurology, Washington University School of Medicine, St. Louis, MO, USA.ORCID 0000-0002-7972-1200
Alex W K WongProgram in Occupational Therapy, Department of Neurology & Department of Psychiatry, Washington University School of Medicine, St. Louis, MO, USA.ORCID 0000-0002-4423-2685
Washington University in St. Louis · US

Funding

Washington University Center for Diabetes Translation Research P30DK092950 · NIDDK · WASHINGTON UNIVERSITY · PI Ross C Brownson, Debra Haire-Joshu · 2011 to 2026
$11.7M
Technique Development CoreP2CHD065702 · NICHD · UNIVERSITY OF TEXAS MED BR GALVESTON · PI OTTENBACHER, KENNETH J. · 2015 to 2019
$5.2M
Mobile Rehabilitation for Daily Life Participation Post-StrokeK01HD095388 · NICHD · WASHINGTON UNIVERSITY · PI WONG, WING KAI · 2019 to 2023
$642k
NICHD NIH HHS K01 HD095388NICHD NIH HHS P2C HD065702NIDDK NIH HHS P30 DK092950
6 · The paper itself

Abstract

objectiveTo compare the effectiveness of non-pharmacological interventions on depressive symptoms in people after stroke. DATA SOURCES: A literature search was performed through databases from January 2000 to August 2018: MEDLINE; CINAHL Plus; Scopus; Academic Search Complete; Cochrane Central Register of Controlled Trials; Scopus; and Library, Information Science and Technology Abstracts. Search terms included depression, stroke, non-pharmacologic, and intervention. STUDY SELECTION: We included randomized controlled trials comparing non-pharmacological interventions to controls for depressive symptoms in people after stroke. Of 1703 identified articles, 22 trials were included in narrative synthesis, of which 13 were eligible for meta-analysis. DATA EXTRACTION: Two reviewers extracted characteristics of participants, interventions, and results from all included trials. DATA SYNTHESIS: Thirteen interventions were categorized into four types: complementary and alternative therapy (five trials, n=228), exercise (four trials, n=263), psychosocial therapy (two trials, n=216), and multifactorial therapy (two trials, n=358). Overall beneficial effects of non-pharmacological interventions on depressive symptoms were found both post-intervention (effect size [ES] = -0.24, 95% confidence Interval [CI]: -0.37 to -0.11,

conclusionsComplementary and alternative therapy and psychosocial therapy appear to be promising strategies for improving post-stroke depression. Future studies target  a personalized approach for people with specific conditions such as cognitive impairment.

Indexed as

DepressionStrokeHumansPsychotherapyRandomized Controlled Trials as Topicbehavior therapycomplementary therapiesdepressionmeta-analysisneuropsychiatryNon-pharmacological interventionspsychosocial therapystrokesystematic review

Identifiers

PMID32783504
PMCPMC7878573
OpenAlexW3048804704

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.