Evidence map›Paper›PMID 32783415›Full record

ArticleKorean journal of radiology2020

Histological Validation of Cardiovascular Magnetic Resonance T1 Mapping for Assessing the Evolution of Myocardial Injury in Myocardial Infarction: An Experimental Study.

Lu Zhang, Zhi Gang Yang, Huayan Xu, Meng Xi Yang, Rong Xu, Lin Chen, Ran Sun, Tianyu Miao, Jichun Zhao, Xiaoyue Zhou and 2 more

Abstract read
In one paragraph

Article in Korean journal of radiology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed.

  1. Trial
  2. Article
  3. Article
  4. Article
  5. Article
  6. Review
  7. Article
  8. Article
  9. Article
  10. Observational
  11. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Lu Zhang *Department of Radiology, Key Laboratory of Birth Defects and Related Diseases of Women and Children of Ministry of Education, West China Second University Hospital, Sichuan University, Chengdu, China.ORCID 0000-0002-0307-7113
Zhi Gang Yang *Department of Radiology, West China Hospital, Sichuan University, Chengdu, China.ORCID 0000-0001-9341-7697
Huayan XuDepartment of Radiology, Key Laboratory of Birth Defects and Related Diseases of Women and Children of Ministry of Education, West China Second University Hospital, Sichuan University, Chengdu, China.ORCID 0000-0001-7276-6142
Meng Xi YangDepartment of Radiology, West China Hospital, Sichuan University, Chengdu, China.ORCID 0000-0001-9780-3536
Rong XuDepartment of Radiology, Key Laboratory of Birth Defects and Related Diseases of Women and Children of Ministry of Education, West China Second University Hospital, Sichuan University, Chengdu, China.ORCID 0000-0001-5974-1258
Lin ChenDepartment of Radiology, Key Laboratory of Birth Defects and Related Diseases of Women and Children of Ministry of Education, West China Second University Hospital, Sichuan University, Chengdu, China.ORCID 0000-0002-2093-1801
Ran SunKey Laboratory of Obstetrics & Gynecology and Pediatric Disease and Birth Defects of Ministry of Education, West China Second University Hospital, Sichuan University, Chengdu, China.ORCID 0000-0003-2621-2733
Tianyu MiaoVascular Surgery, West China Hospital, Sichuan University, Chengdu, China.ORCID 0000-0002-3762-7937
Jichun ZhaoVascular Surgery, West China Hospital, Sichuan University, Chengdu, China.ORCID 0000-0002-8846-682X
Xiaoyue ZhouSiemens Healthineers Ltd., Shanghai, China.ORCID 0000-0002-7094-4731
Chuan FuDepartment of Radiology, West China Second Hospital, Sichuan University, Chengdu, China.ORCID 0000-0001-9737-0806
Yingkun GuoDepartment of Radiology, Key Laboratory of Birth Defects and Related Diseases of Women and Children of Ministry of Education, West China Second University Hospital, Sichuan University, Chengdu, China. gykpanda@163.com.ORCID 0000-0001-8437-9887

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveTo determine whether T1 mapping could monitor the dynamic changes of injury in myocardial infarction (MI) and be histologically validated. MATERIALS AND

methodsIn 22 pigs, MI was induced by ligating the left anterior descending artery and they underwent serial cardiovascular magnetic resonance examinations with modified Look-Locker inversion T1 mapping and extracellular volume (ECV) computation in acute (within 24 hours, n = 22), subacute (7 days, n = 13), and chronic (3 months, n = 7) phases of MI. Masson's trichrome staining was performed for histological ECV calculation. Myocardial native T1 and ECV were obtained by region of interest measurement in infarcted, peri-infarct, and remote myocardium.

resultsNative T1 and ECV in peri-infarct myocardium differed from remote myocardium in acute (1181 ± 62 ms vs. 1113 ± 64 ms,

conclusionT1 mapping allows the quantitative assessment of injury in MI and the noninvasive monitoring of tissue injury evolution, which correlates well with histological findings.

Indexed as

Acute DiseaseAnimalsChronic DiseaseContrast MediaDisease Models, AnimalImage Processing, Computer-AssistedMagnetic Resonance Imaging, CineMaleMyocardial InfarctionMyocardiumReproducibility of ResultsSwineContrast MediaCardiacCardiovascular magnetic resonanceHistologyMyocardial infarctionT1 mapping

Identifiers

PMID32783415
PMCPMC7689143

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.