Evidence map›Paper›PMID 32783205›Full record

ArticleThe Journal of comparative neurology2021

The SNARE regulator Complexin3 is a target of the cone circadian clock.

Jacob D Bhoi, Zhijing Zhang, Roger Janz, Yanan You, Haichao Wei, Jiaqian Wu, Christophe P Ribelayga

Open access · greenAbstract read
In one paragraph

Article in The Journal of comparative neurology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
0.4field-weighted citation impact, top 47% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 8 citations in OpenAlex.

  1. Review
  2. Review
  3. Syntaxin 3B: A SNARE Protein Required for Vision.International journal of molecular sciences · 2024
    Review
  4. Article
  5. Article
  6. Review
  7. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 1 country.

Jacob D BhoiRice University, Undergraduate Program in Neuroscience, Houston, Texas, USA.
Zhijing ZhangRuiz Department of Ophthalmology and Visual Science, McGovern Medical School, The University of Texas Health Science Center at Houston, Houston, Texas, USA.
Roger JanzDepartment of Neurobiology and Anatomy, McGovern Medical School, The University of Texas Health Science Center at Houston, Houston, Texas, USA.
Yanan YouThe Vivian L. Smith Department of Neurosurgery, McGovern Medical School, The University of Texas Health Science Center at Houston, Houston, Texas, USA.
Haichao WeiThe Vivian L. Smith Department of Neurosurgery, McGovern Medical School, The University of Texas Health Science Center at Houston, Houston, Texas, USA.
Jiaqian WuMD Anderson UTHealth Graduate School of Biomedical Sciences, The University of Texas Health Science Center at Houston, Houston, Texas, USA.
Christophe P RibelaygaSummer Research Program, McGovern Medical School, The University of Texas Health Science Center at Houston, Houston, Texas, USA.ORCID 0000-0001-5889-2070
The University of Texas Health Science Center · USBrown Foundation · US

Funding

Center for Clinical and Translational Sciences (CCTS)UL1TR000371 · NCATS · UNIVERSITY OF TEXAS HLTH SCI CTR HOUSTON · PI MCPHERSON, DAVID D · 2012 to 2016
$13.4M
Identifying Novel Molecular Targets for Chronic SCIR01NS088353 · NINDS · UNIVERSITY OF TEXAS HLTH SCI CTR HOUSTON · PI JIaqian Wu-Huber · 2015 to 2026
$4.0M
UTHouston Core Center for Vision ResearchP30EY028102 · NEI · UNIVERSITY OF TEXAS HLTH SCI CTR HOUSTON · PI MASSEY, STEPHEN C · 2017 to 2021
$3.1M
Rod/cone gap junctions initiate an irradiance pathwayR01EY029408 · NEI · UNIVERSITY OF TEXAS HLTH SCI CTR HOUSTON · PI MASSEY, STEPHEN C, RIBELAYGA, CHRISTOPHE P. · 2018 to 2022
$2.9M
The role of circadian clocks in photoreceptor cell development, maintenance and functionR21EY028647 · NEI · UNIVERSITY OF TEXAS HLTH SCI CTR HOUSTON · PI RIBELAYGA, CHRISTOPHE P., WU-HUBER, JIAQIAN · 2018 to 2019
$424k
NCATS NIH HHS UL1 TR000371NEI NIH HHS P30 EY028102NEI NIH HHS R01 EY029408NEI NIH HHS R21 EY028647
6 · The paper itself

Abstract

BMAL1 is a core component of the mammalian circadian clockwork. Removal of BMAL1 from the retina significantly affects visual information processing in both rod and cone pathways. To identify potential pathways and/or molecules through which BMAL1 alters signal transmission at the cone pedicle, we performed an RNA-seq differential expression analysis between cone-specific Bmal1 knockout cones (cone-Bmal1

Indexed as

Adaptor Proteins, Signal TransducingAdaptor Proteins, Vesicular TransportAnimalsARNTL Transcription FactorsCircadian ClocksDown-RegulationFemaleMaleMiceMice, KnockoutNerve Tissue ProteinsPromoter Regions, GeneticRetinal Cone Photoreceptor CellsRetinal PigmentsRNA, MessengerRNA-SeqAdaptor Proteins, Signal TransducingAdaptor Proteins, Vesicular TransportARNTL Transcription FactorsBmal1 protein, mouseCplx3 protein, mouseNerve Tissue ProteinsRetinal PigmentsRNA, MessengerSensory RhodopsinsSNARE ProteinsBmal1circadian clockconesCplx3Cplx4retinaribbon synapsesSNARE proteins

Identifiers

PMID32783205
PMCPMC8190822
OpenAlexW3048830349

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.