Evidence map›Paper›PMID 32783135›Full record

ArticleJournal of assisted reproduction and genetics2020

Association between long-chain non-coding RNA SRA1 gene single-nucleotide polymorphism and polycystic ovary syndrome susceptibility.

Jifan Tan, XiuLan Hao, TingTing Zhao, JianLan Ying, Tian Li, Li Cheng

Open access · bronzeAbstract read
In one paragraph

Article in Journal of assisted reproduction and genetics, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
0.2field-weighted citation impact, top 53% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 9 citations in OpenAlex.

  1. Article
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  5. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Jifan TanDepartment of Obstetrics and Gynecology, The Seventh Affiliated Hospital of Sun Yat-sen University, Shenzhen, 518107, China.ORCID http://orcid.org/0000-0002-1589-3599
XiuLan HaoDepartment of Obstetrics and Gynecology, The Seventh Affiliated Hospital of Sun Yat-sen University, Shenzhen, 518107, China.
TingTing ZhaoDepartment of Obstetrics and Gynecology, The Seventh Affiliated Hospital of Sun Yat-sen University, Shenzhen, 518107, China.
JianLan YingDepartment of Obstetrics and Gynecology, The Seventh Affiliated Hospital of Sun Yat-sen University, Shenzhen, 518107, China.
Tian LiDepartment of Obstetrics and Gynecology, The Seventh Affiliated Hospital of Sun Yat-sen University, Shenzhen, 518107, China. sandylitian@126.com.
Li ChengDepartment of Obstetrics and Gynecology, The Seventh Affiliated Hospital of Sun Yat-sen University, Shenzhen, 518107, China. cl0926@126.com.
Sun Yat-sen University · CN

Funding

Natural Science Foundation of Guangdong Province 2018A030313735
6 · The paper itself

Abstract

objectiveTo study the association between single-nucleotide polymorphism (SNP) of long-chain non-coding RNA steroid receptor RNA activator (lncRNA SRA1) gene and polycystic ovary syndrome (PCOS) susceptibility.

methodsSanger sequencing was used to analyze the genotypes of the lncRNA SRA1 gene rs801460, rs10463297, and rs250426 in 315 PCOS patients and 315 control groups.

resultsThere was no correlation between lncRNA SRA1 gene rs801460, rs250426 SNP, and PCOS susceptibility (p > 0.05). The T allele at the rs10463297 locus of the SRA1 gene has a lower risk of PCOS than the C allele (OR = 0.63, 95%CI: 0.50-0.79, p < 0.01). Among people with a BMI ≥ 26.5 kg/m

conclusionFrom this study, we found that the lncRNA SRA1 gene rs10463297 SNP is associated with PCOS susceptibility.

Indexed as

Genetic Predisposition to DiseaseAdultAllelesAsian PeopleCarrier ProteinsFemaleGene FrequencyGenetic Association StudiesGenotypeHaplotypesHumansPolycystic Ovary SyndromePolymorphism, Single NucleotideRNA, Long NoncodingCarrier ProteinsRNA, Long Noncodingsteroid receptor RNA activator, humanLong noncoding RNAPolycystic ovary syndromeSingle-nucleotide polymorphismSteroid receptor RNA activator

Identifiers

PMID32783135
PMCPMC7550517
OpenAlexW3048487658

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.