ArticleJGH open : an open access journal of gastroenterology and hepatology2020
Portal vein flow velocity as a possible fast noninvasive screening tool for esophageal varices in cirrhotic patients.
Article in JGH open : an open access journal of gastroenterology and hepatology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.
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7 citing papers in PubMed, 15 citations in OpenAlex.
- Endoscopic ultrasound vascular parameter-based stratification for precise treatment of esophagogastric varices: a study on endoscopic ultrasound-guided tissue glue obliteration.Surgical endoscopy · 2026Article
- A portal into hemodynamics: utility of portal vein ultrasound in predicting variceal etiology of upper gastrointestinal hemorrhage in the emergency department.Internal and emergency medicine · 2025Article
- Doppler ultrasound and 2D shear wave ultrasound elastography for liver fibrosis evaluation in Fontan-associated liver disease.BMC gastroenterology · 2025Article
- Measurement of portal vein indices and splenic index by ultrasound and their association with gastroesophageal varices in cirrhosis of liver.Annals of medicine and surgery (2012) · 2023Article
- Diagnostic Accuracy of Portal Vein Flow Velocity for Esophageal Varices in Cirrhotic Patients.Cureus · 2023Article
- Comparison of portal vein hemodynamics with ultrasound-based elastography for the prediction of liver fibrosis in patients with chronic liver disease.Scientific reports · 2023Article
- Noninvasive imaging of hepatic dysfunction: A state-of-the-art review.World journal of gastroenterology · 2022Review
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4 authors at 1 institution in 1 country.
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Abstract
BACKGROUND AND
aimEsophagogastroduodenoscopy (EGD) is the gold standard tool in both screening/diagnosis and management of varices in cirrhotic patients; however, its invasive nature may be uncomfortable to some patients, and in addition, it may be unavailable in some centers that cannot afford it. Therefore, to decrease the economic and physical burden on patients, multiple noninvasive clinical, laboratory, and radiological parameters are evaluated as triage screening predictors of varices before patients' referral to endoscopy. In this respect, we tried to evaluate the validity of portal vein velocity (PVV) as a noninvasive screening tool of esophageal varices (EV).
methodsOne hundred thirty-five cirrhotic patients were consecutively enrolled in this cross-sectional study. All patients were evaluated independently and blindly by EGD as the gold standard and then by Doppler ultrasound on portal vein (PV).
resultsUnivariate regression showed significant coefficients for PVV, platelet (PLT), albumin, bilirubin, international normalized ratio (INR), portal vein diameter, and ascites; however, multivariable regression showed significant coefficients only for PVV, PLT, and albumin; (
conclusionPVV may be useful as a noninvasive triage test for selection of the high-risk cirrhotic patients who should be referred to and could benefit from EGD. We could highlight using PVV to rule out EV at a cutoff value ≥19 cm/s, reserving EGD only for patients with the PVV value <19 cm/s.
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