Evidence map›Paper›PMID 32782871›Full record

ArticleCureus2020

Platypnea-Orthodeoxia Syndrome: A Rare and Treatable Cause of Positional Dyspnea.

Karan Puri, Ghulam Aftab, Arjun Madhavan, Keval V Patel, Megha Puri

Abstract readCase Reports
In one paragraph

Article in Cureus, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Karan PuriInternal Medicine, Saint Peter's University Hospital, New Brunswick, USA.
Ghulam AftabPulmonary Medicine, Saint Peter's University Hospital, New Brunswick, USA.
Arjun MadhavanCritical Care, Saint Peter's University Hospital, New Brunswick, USA.
Keval V PatelCardiology, Saint Peter's University Hospital, New Brunswick, USA.
Megha PuriPathology, Pandit Bhagwat Dayal Sharma University of Health Sciences, Rohtak, IND.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Platypnea-orthodeoxia means low oxygen saturation and dyspnea in the upright posture which improves on lying down. The causes can be classified into the intrapulmonary shunt, intracardiac shunt, and ventilation-perfusion mismatch. A 62-year-old male presented with shortness of breath, which had worsened over a period of one year. Various investigations were done to rule bacterial, viral infection, pulmonary embolism, and other respiratory and cardiac causes. The initial echocardiogram showed an ejection fraction of 55%. The patient was observed to be having dyspnea only in the upright position. In the recumbent position, the dyspnea disappeared with a marked improvement in oxygen saturation. A repeat echocardiogram with a bubble study was done which showed an atrial septal defect. Surgical closure of the defect was performed which improved the patient's oxygen saturation to baseline normal. This case demonstrates that a vigilant approach is required in cases of dyspnea, keeping in mind the not-so-common phenomenon like platypnea-orthodeoxia syndrome.

Indexed as

hyperoxia testintracardiac shuntsintrapulmonary shuntsorthodeoxiaplatypnea

Identifiers

PMID32782871
PMCPMC7410398

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.