Evidence map›Paper›PMID 32782814›Full record

ArticleCanadian journal of kidney health and disease2020

COVID-19 Outbreak in a Hemodialysis Center: A Retrospective Monocentric Case Series.

Lionel Mazzoleni, Chadi Ghafari, Fabienne Mestrez, Roxana Sava, Elena Bivoleanu, Philippe Delmotte, France Laurent, Thomas Roland, Camelia Rossi, Stéphane Carlier

Open access · goldAbstract read
In one paragraph

Article in Canadian journal of kidney health and disease, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed, 3 pooled it
0.5field-weighted citation impact, top 21% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

18 citing papers in PubMed, 3 syntheses or guidelines pooled it, 21 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Pooled it
  4. Article
  5. Article
  6. Clinical manifestations of COVID-19 infection in dialysis patients and protective effect of COVID-19 vaccine.Inflammation research : official journal of the European Histamine Research Society ... [et al.] · 2023
    Review
  7. Observational
  8. Article
  9. Article
  10. Severity of COVID-19 in end-stage kidney disease patients on chronic dialysis.Therapeutic apheresis and dialysis : official peer-reviewed journal of the International Society for Apheresis, the Japanese Society for Apheresis, the Japanese Society for Dialysis Therapy · 2021
    Article
  11. Article
  12. Low seroprevalence of SARS-CoV-2 antibodies in a liver transplant cohort.Transplant international : official journal of the European Society for Organ Transplantation · 2021
    Article
  13. CMAJ : Canadian Medical Association journal = journal de l'Association medicale canadienne · 2021
    Article
  14. COVID-19 in patients undergoing long-term dialysis in Ontario.CMAJ : Canadian Medical Association journal = journal de l'Association medicale canadienne · 2021
    Article
  15. Article
  16. Article
  17. Expecting the unexpected: COVID-19 in Kidney Transplant Recipients within United Network for Organ Sharing Region 1.Transplant international : official journal of the European Society for Organ Transplantation · 2020
    Article
  18. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 2 institutions in 1 country.

Lionel MazzoleniDepartment of Nephrology, Centre Hospitalier Universitaire et Psychiatrique de Mons-Borinage, Belgium.ORCID https://orcid.org/0000-0002-0154-7812
Chadi GhafariDepartment of Cardiology, Université de Mons, Belgium.ORCID https://orcid.org/0000-0002-5971-5073
Fabienne MestrezDepartment of Nephrology, Centre Hospitalier Universitaire et Psychiatrique de Mons-Borinage, Belgium.
Roxana SavaDepartment of Nephrology, Centre Hospitalier Universitaire et Psychiatrique de Mons-Borinage, Belgium.
Elena BivoleanuDepartment of Endocrinology, Centre Hospitalier Universitaire et Psychiatrique de Mons-Borinage, Belgium.
Philippe DelmotteDepartment of Cardiology, Université de Mons, Belgium.
France LaurentDepartment of Infectious Disease, Centre Hospitalier Universitaire et Psychiatrique de Mons-Borinage, Belgium.
Thomas RolandDepartment of Infectious Disease, Centre Hospitalier Universitaire et Psychiatrique de Mons-Borinage, Belgium.
Camelia RossiDepartment of Infectious Disease, Centre Hospitalier Universitaire et Psychiatrique de Mons-Borinage, Belgium.
Stéphane CarlierDepartment of Cardiology, Université de Mons, Belgium.ORCID https://orcid.org/0000-0001-7787-1937
Centre Hospitalier Universitaire de Liège · BEUniversity of Mons · BE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThe rapid worldwide spread of COVID-19 has posed a serious threat to patients treated with kidney replacement therapy (KRT). Moreover, the impact of the disease on hemodialysis centers, the patients, and the health care workers is still not completely understood.

objectiveWe present the analysis of a COVID-19 outbreak in a hemodialysis center in Belgium and report the incidence, clinical course, and outcome of the disease.

designA retrospective cross-sectional cohort study.

settingA hemodialysis center during the COVID-19 outbreak. PATIENTS: A total of 62 patients on maintenance hemodialysis at a tertiary care center in Belgium attended by 26 health care workers. MEASUREMENTS: Baseline patients' characteristics were retrieved. The incidence, clinical course, and outcome were reported. The differences between COVID-19 survivors and nonsurvivors were assessed along with the differences between COVID-19-hospitalized and nonhospitalized patients. The incidence of the disease and outcome of health care workers were also reported.

methodsProportions for categorical variables were compared using the Fisher exact test and χ

resultsBetween March 6 and April 14, 2020, 40 of 62 (65%) patients tested positive for severe acute respiratory syndrome beta coronavirus 2 (SARS-CoV-2) along with 18 of 26 (69%) health care professionals. Twenty-five (63%) of the infected patients were hospitalized with a median time for hospitalization-to-discharge of 8 (interquartile range [IQR] = 4-12) days. Eleven (28%) COVID-19-related deaths were recorded with a median time for onset of symptoms-to-death of 9 (IQR = 5-14) days. Lymphocytopenia was prevalent among the cohort and was found in 9 of 11 (82%) reported deaths ( LIMITATIONS: Limited follow-up time compared with the course of the disease along with a small sample size.

conclusionsPatients treated with KRT show a high mortality rate secondary to COVID-19. CVD and age are shown to impact survival. Proactive measures must be taken to prevent the spread of the virus in such facilities.

trial registrationNot applicable as this is a retrospective study.

Indexed as

COVID-19end-stage kidney diseasehemodialysishemodialysis centermortalitySARS-CoV2

Identifiers

PMID32782814
PMCPMC7383633
OpenAlexW3044787882

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.