ArticleEuropean journal of translational myology2020
Increase of resting muscle stiffness, a less considered component of age-related skeletal muscle impairment.
Article in European journal of translational myology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 37 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
37 citing papers in PubMed, 1 synthesis or guideline pooled it, 34 citations in OpenAlex.
- Muscle elasticity variations in assessing age-related changes in adults - A systematic review.Geriatrics & gerontology international · 2025Pooled it
- Treating age-related loss of muscle mass and function: Where should we be focusing?The Journal of physiology · 2026Review
- Aging in motion: how age and age simulation shape dual-task walking and memory.European review of aging and physical activity : official journal of the European Group for Research into Elderly and Physical Activity · 2026Article
- Sex-specific effects of fatiguing exercise on skeletal muscle passive mechanics are preserved in aging.bioRxiv : the preprint server for biology · 2026Article
- Regional Differences in Muscle and Fascial Tissue Stiffness in the Rectus Femoris Are Dependent Upon Localised Stretching.European journal of sport science · 2026Article
- Thermal Responses to Exercise in Male Master Track & Field Athletes: Monitoring during Competition.Journal of human kinetics · 2026Article
- Mechano-immune interactions in musculoskeletal aging: Mechanisms and translational perspectives.Theranostics · 2026Review
- Article
- Age-related changes in quadriceps stiffness and strength: a longitudinal observation in community-dwelling older adults.BMC geriatrics · 2025Observational
- Discovery and Treatment of Action Potential-Independent Myotonia in Hyperkalemic Periodic Paralysis.Annals of clinical and translational neurology · 2025Article
- Aging-related changes in neuromuscular control strategies and their influence on postural stability.Scientific reports · 2025Article
- The role of physical activity in mitigating age-related changes in the neuromuscular control of gait.npj aging · 2025Article
- The effects of series elastic stiffness and cutaneous sensitivity on leg muscle reflex responses to unanticipated slips during walking.Experimental brain research · 2025Article
- The Utilization and Impact of Dopamine Transporter Imaging in Diagnosing Movement Disorders at a Tertiary Care Hospital in Greece.Biomedicines · 2025Article
- Evaluation of a Novel Method for Temporary Eyebrow Lifting Using Polydioxanone Threads: Preliminary Findings.Journal of clinical medicine · 2025Article
- From molecular to physical function: The aging trajectory.Current research in physiology · 2025Review
- Dantrolene-Responsive Muscle Stiffness in a Patient With a Normal Neurologic Exam and EMG: A Case Report.Case reports in neurological medicine · 2025Article
- Aging-associated differences between perioral and trunk muscle characteristics.Scientific reports · 2024Article
- Association of Muscle Quality and Pain in Adults With Symptomatic Knee Osteoarthritis, Independent of Muscle Strength: Findings From a Cross-Sectional Study.Arthritis & rheumatology (Hoboken, N.J.) · 2024Article
- The effects of myosteatosis on skeletal muscle function in older adults.Physiological reports · 2024Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors at 1 institution in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Elderly people perform more slowly movements of everyday life as rising from a chair, walking, and climbing stairs. This is in the first place due to the loss of muscle contractile force which is even more pronounced than the loss of muscle mass. In addition, a secondary, but not negligible, component is the rigidity or increased stiffness which requires greater effort to produce the same movement and limits the range of motion of the joints. In this short review, we discuss the possible determinants of the limitations of joint mobility in healthy elderly, starting with the age-dependent alterations of the articular structure and focusing on the increased stiffness of the skeletal muscles. Thereafter, the possible mechanisms of the increased stiffness of the muscle-tendon complex are considered, among them changes in the muscle fibers, alterations of the connective tissue components, i.e., extracellular matrix (ECM), aponeurosis, tendon and fascia, and remodeling of the neural pattern of muscle activation that increases antagonist co-activation.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.