ArticleInternational journal of clinical and experimental pathology2020
Gene expression analysis of primary gingival cancer by whole exome sequencing in thirteen Chinese patients.
Article in International journal of clinical and experimental pathology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
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Who cites it
1 citing paper in PubMed, 1 citations in OpenAlex.
- Evidence of mutations in tumour suppressor genes among oral cancer in Naswar, smokeless tobacco users.Acta odontologica Scandinavica · 2025Article
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Authors and funding
4 authors at 1 institution in 1 country.
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Abstract
objectivesEarly diagnosis of and markers for gingival oral squamous cell carcinoma (OSCC) is important for effective treatment.
methodsThe current study performed a whole exome sequencing of gingival OSCC tissues in thirteen Chinese patients to explore exonic mutants.
resultsEighty-five genes emerged as mutants in patients with primary gingival OSCC. CCL4L1 presented a G>A transversion at chr17 17q12, position 36212480, exon 3. KDM5B presented a T>TA insertion at chr1 1q32.1, position 202766506, exon 6. ANKRD36C presented a C>G transition at chr2 2q11.1, position 95945175, exon 18.
conclusionThese three mutants might be new markers of gingival OSCC. The finding may provide new targets to diagnose and treat gingival OSCC.
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Identifiers
32782722PMC7414513W3048501980What OpenQuestion holds
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