ArticleInternational journal of clinical and experimental pathology2020
Role of NLRP3 inflammasome in the obesity paradox of rats with ventilator-induced lung injury.
Article in International journal of clinical and experimental pathology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
2 citing papers in PubMed, 3 citations in OpenAlex.
- Obesity Paradox in Lung Diseases: What Explains It?Obesity facts · 2023Review
- Aerobic exercise alleviates ventilator-induced lung injury by inhibiting NLRP3 inflammasome activation.BMC anesthesiology · 2022Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The objective of this research is to determine the action of the nucleotide oligomerization domain-like receptors containing pyrin domain 3 (NLRP3) inflammasome in the obesity paradox of rats with ventilator-induced lung injury (VILI). Twenty-four (average weight: 250 ± 20 g) pathogen-free adult male Sprague Dawley (SD) rats were randomly classified as group A and group B, while twelve obese (420 ± 20 g) pathogen-free adult male SD rats were classified as group C. Three groups received open tracheotomies after anesthesia. Group A then underwent spontaneous breathing for 4 h after endotracheal intubation, and group B and group C were then connected to a ventilator to administer high tidal volume ventilation (V
Indexed as
Identifiers
32782709PMC7414485W3048746409What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.