ArticleJournal of arrhythmia2020
Diverse activation patterns during persistent atrial fibrillation by noncontact charge-density mapping of human atrium.
Article in Journal of arrhythmia, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
11 citing papers in PubMed, 17 citations in OpenAlex.
- Multi-modal integration of MRI and global chamber charge density mapping for the evaluation of atrial fibrillation.Royal Society open science · 2025Article
- Electroanatomical Conduction Characteristics of Pig Myocardial Tissue Derived from High-Density Mapping.Journal of clinical medicine · 2023Article
- Electrocardiographic imaging in the atria.Medical & biological engineering & computing · 2023Review
- Atrial Fibrillation Global Changes after Pulmonary Vein and Posterior Wall Isolation: A Charge Density Mapping Study.Journal of clinical medicine · 2022Article
- Global Substrate Mapping and Targeted Ablation with Novel Gold-tip Catheter inArrhythmia & electrophysiology review · 2022Review
- Characterization of persistent atrial fibrillation with non-contact charge density mapping and relationship to voltage.Journal of arrhythmia · 2022Article
- Substrate mapping of the left atrium in persistent atrial fibrillation: spatial correlation of localized complex conduction patterns in global charge-density maps to low-voltage areas in 3D contact bipolar voltage maps.Journal of interventional cardiac electrophysiology : an international journal of arrhythmias and pacing · 2021Article
- Spatial and temporal variability of rotational, focal, and irregular activity: Practical implications for mapping of atrial fibrillation.Journal of cardiovascular electrophysiology · 2021Article
- Is there rule to the chaos: Defining stable patterns in atrial fibrillation.Journal of cardiovascular electrophysiology · 2021Article
- Editorial to "Diverse activation patterns during persistent atrial fibrillation by non-contact charge-density mapping of human atrium".Journal of arrhythmia · 2020Article
- Diverse activation patterns during persistent atrial fibrillation by noncontact charge-density mapping of human atrium.Journal of arrhythmia · 2020Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
14 authors at 2 institutions in 3 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundGlobal simultaneous recording of atrial activation during atrial fibrillation (AF) can elucidate underlying mechanisms contributing to AF maintenance. A better understanding of these mechanisms may allow for an individualized ablation strategy to treat persistent AF. The study aims to characterize left atrial endocardial activation patterns during AF using noncontact charge-density mapping.
methodsTwenty-five patients with persistent AF were studied. Activation patterns were characterized into three subtypes: (i) focal with centrifugal activation (FCA); (ii) localized rotational activation (LRA); and (iii) localized irregular activation (LIA). Continuous activation patterns were analyzed and distributed in 18 defined regions in the left atrium.
resultsA total of 144 AF segments with 1068 activation patterns were analyzed. The most common pattern during AF was LIA (63%) which consists of four disparate features of activation: slow conduction (45%), pivoting (30%), collision (16%), and acceleration (7%). LRA was the second-most common pattern (20%). FCA accounted for 17% of all activations, arising frequently from the pulmonary veins (PVs)/ostia. A majority of patients (24/25; 96%) showed continuous and highly dynamic patterns of activation comprising multiple combinations of FCA, LRA, and LIA, transitioning from one to the other without a discernible order. Preferential conduction areas were typically seen in the mid-anterior (48%) and lower-posterior (40%) walls.
conclusionAtrial fibrillation is characterized by heterogeneous activation patterns identified in PV-ostia and non-PV regions throughout the LA at varying locations between individuals. Clinical implications of individualized ablation strategies guided by charge-density mapping need to be determined.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.