Evidence map›Paper›PMID 32782323›Full record

Trial reportJournal of perinatology : official journal of the California Perinatal Association2021

The effect of umbilical cord milking on cerebral blood flow in very preterm infants: a randomized controlled study.

Walid El-Naggar, Douglas McMillan, Arif Hussain, Anthony Armson, Andrew Warren, Robin Whyte, David Simpson

Registry-linked trialAbstract readRandomized Controlled Trial
PubMed Publisher
In one paragraph

Trial report in Journal of perinatology : official journal of the California Perinatal Association, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT01487187 (The Effect of Umbilical Cord Milking on Hemodynamic Status of Preterm Infants), which is not on this map. Cited by 2 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed, 1 pooled it
0.9field-weighted citation impact, top 22% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT01487187 naunknown statusnot on this map

The Effect of Umbilical Cord Milking on Hemodynamic Status of Preterm Infants: a Randomized Controlled Trial

TypeinterventionalSponsorWalid El-NaggarRan2011 to 2018Enrolled73ConditionsPreterm InfantsArmsMilking the umbilical cord at birth, immediate umbilical cord clamping
3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 1 synthesis or guideline pooled it, 7 citations in OpenAlex.

  1. Pooled it
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

Walid El-NaggarDivision of Neonatal-Perinatal Medicine, Department of Pediatrics, Dalhousie University, Halifax, Canada. walid.el-naggar@iwk.nshealth.ca.ORCID http://orcid.org/0000-0001-6657-4507
Douglas McMillanDivision of Neonatal-Perinatal Medicine, Department of Pediatrics, Dalhousie University, Halifax, Canada.
Arif HussainDivision of Cardiology, Department of Pediatrics, Dalhousie University, Halifax, Canada.
Anthony ArmsonDepartment of Obstetrics & Gynecology, Dalhousie University, Halifax, Canada.
Andrew WarrenDivision of Cardiology, Department of Pediatrics, Dalhousie University, Halifax, Canada.
Robin WhyteDivision of Neonatal-Perinatal Medicine, Department of Pediatrics, Dalhousie University, Halifax, Canada.
David SimpsonDivision of Neonatal-Perinatal Medicine, Department of Pediatrics, Dalhousie University, Halifax, Canada.
Dalhousie University · CA

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveTo compare the effect of umbilical cord milking (UCM) vs. early cord clamping (ECC) on cerebral blood flow (CBF).

methodPreterm infants <31 weeks' gestation were randomized to receive UCM or ECC at birth. Blood flow velocities and resistive & pulsatility indices of middle and anterior cerebral arteries were measured at 4-6 and 10-12 h after birth as an estimate of CBF.

resultsRandomization allocated 37 infants to UCM and 36 to ECC. Maternal and antenatal variables were similar. There were no significant differences between groups in middle or anterior CBF velocities and resistive indices at either study time point. CBF variables were not correlated with mean blood pressure, systemic blood flow, or intraventricular hemorrhage.

conclusionsIn very preterm infants, UCM compared with ECC was not shown to change CBF indices during the first 12 h of age or correlate with other hemodynamic measures or with intraventricular hemorrhage.

trial registrationClinicalTrials.gov: NCT01487187.

Indexed as

Infant, PrematureInfant, Premature, DiseasesCerebrovascular CirculationConstrictionFemaleHumansInfantInfant, NewbornPregnancyUmbilical Cord

Identifiers

PMID32782323
OpenAlexW3048586356

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.