ArticleThe Journal of laryngology and otology2020
Smell and taste recovery in coronavirus disease 2019 patients: a 60-day objective and prospective study.
Article in The Journal of laryngology and otology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 103 papers, 9 of them syntheses that pooled it.
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Who cites it
103 citing papers in PubMed, 9 syntheses or guidelines pooled it.
- Taste loss as a distinct symptom of COVID-19: a systematic review and meta-analysis.Chemical senses · 2023Pooled it
- Neurological and Head/Eyes/Ears/Nose/Throat Manifestations of COVID-19: A Systematic Review and Meta-Analysis.The Canadian journal of neurological sciences. Le journal canadien des sciences neurologiques · 2022Pooled it
- Symptoms and signs of long COVID: A rapid review and meta-analysis.Journal of global health · 2022Pooled it
- Short-term and Long-term Rates of Postacute Sequelae of SARS-CoV-2 Infection: A Systematic Review.JAMA network open · 2021Pooled it
- Assessment of the Frequency and Variety of Persistent Symptoms Among Patients With COVID-19: A Systematic Review.JAMA network open · 2021Pooled it
- Pooled it
- Post-COVID-19 Syndrome: The Persistent Symptoms at the Post-viral Stage of the Disease. A Systematic Review of the Current Data.Frontiers in medicine · 2021Pooled it
- Pooled it
- Neurological Complications of COVID-19 and Possible Neuroinvasion Pathways: A Systematic Review.International journal of environmental research and public health · 2020Pooled it
- Intensive Olfactory Training in Post-COVID-19 Patients: A Multicenter Randomized Clinical Trial.American journal of rhinology & allergy · 2022Trial
- Enhanced Taste Recognition Following Subacute Treatment With The Dopamine D2/D3 Receptor Agonist Pramipexole in Healthy Volunteers.The international journal of neuropsychopharmacology · 2022Trial
- Ultramicronized Palmitoylethanolamide and Luteolin Supplement Combined with Olfactory Training to Treat Post-COVID-19 Olfactory Impairment: A Multi-Center Double-Blinded Randomized Placebo- Controlled Clinical Trial.Current neuropharmacology · 2022Trial
- Mometasone furoate nasal spray in the treatment of patients with COVID-19 olfactory dysfunction: A randomized, double blind clinical trial.International immunopharmacology · 2021Trial
- Effect of nasal corticosteroid in the treatment of anosmia due to COVID-19: A randomised double-blind placebo-controlled study.American journal of otolaryngologyTrial
- Limited observed efficacy of olfactory training in severe long-term post-COVID-19 syndrome: a prospective cohort study.European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery · 2026Article
- Study of Chemosensory Enhancement through Neuromodulation Training (SCENT): Design and methodology of a randomized clinical trial for COVID-related persistent smell dysfunction.Contemporary clinical trials communications · 2026Article
- Psilocybin-containing mushroom-assisted psychotherapy is associated with sustained psychological and somatic improvements: two case studies from Jamaica.Frontiers in psychiatry · 2026Article
- Impaired metal perception and regulation of associated human foliate papillae tongue transcriptome in long-COVID-19.Scientific reports · 2024Article
- Long-Term Taste and Smell Outcomes After COVID-19.JAMA network open · 2024Article
- Inflammation and olfactory loss are associated with at least 139 medical conditions.Frontiers in molecular neuroscience · 2024Article
43 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
12 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundThe long-term recovery rate of chemosensitive functions in coronavirus disease 2019 patients has not yet been determined.
methodA multicentre prospective study on 138 coronavirus disease 2019 patients was conducted. Olfactory and gustatory functions were prospectively evaluated for 60 days.
resultsWithin the first 4 days of coronavirus disease 2019, 84.8 per cent of patients had chemosensitive dysfunction that gradually improved over the observation period. The most significant increase in chemosensitive scores occurred in the first 10 days for taste and between 10 and 20 days for smell. At the end of the observation period (60 days after symptom onset), 7.2 per cent of the patients still had severe dysfunctions. The risk of developing a long-lasting disorder becomes significant at 10 days for taste (odds ratio = 40.2, 95 per cent confidence interval = 2.204-733.2, p = 0.013) and 20 days for smell (odds ratio = 58.5, 95 per cent confidence interval = 3.278-1043.5, p = 0.005).
conclusionChemosensitive disturbances persisted in 7.2 per cent of patients 60 days after clinical onset. Specific therapies should be initiated in patients with severe olfactory and gustatory disturbances 20 days after disease onset.
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