Evidence map›Paper›PMID 32782001›Full record

ArticleBMC pediatrics2020

Evidence for disruption of diurnal salivary cortisol rhythm in childhood obesity: relationships with anthropometry, puberty and physical activity.

Ting Yu, Wei Zhou, Su Wu, Qianqi Liu, Xiaonan Li

Open access · goldAbstract read
In one paragraph

Article in BMC pediatrics, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.

0numbers the graph read from it
0cells of the map it votes in
19citing papers in PubMed
1.5field-weighted citation impact, top 18% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

19 citing papers in PubMed, 25 citations in OpenAlex.

  1. Article
  2. Observational
  3. Review
  4. Cortisol, dehydroepiandrosterone, and depressive symptoms as pathways from child abuse to obesity.Health psychology : official journal of the Division of Health Psychology, American Psychological Association · 2025
    Article
  5. Article
  6. Article
  7. Longitudinal analysis of cortisol changes during pubertal development in indigenous Qom girls.American journal of human biology : the official journal of the Human Biology Council · 2024
    Article
  8. Article
  9. Metabolic underpinnings of cancer-related fatigue.American journal of physiology. Endocrinology and metabolism · 2024
    Review
  10. Article
  11. Article
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  13. Review
  14. Article
  15. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Ting YuDepartment of Child Health Care, Children's Hospital of Nanjing Medical University, 72 Guangzhou Road, Nanjing, 210008, China.
Wei ZhouDepartment of Child Health Care, Children's Hospital of Nanjing Medical University, 72 Guangzhou Road, Nanjing, 210008, China.
Su WuDepartment of Endocrinology, Children's Hospital of Nanjing Medical University, Nanjing, 210008, China.
Qianqi LiuDepartment of Child Health Care, Children's Hospital of Nanjing Medical University, 72 Guangzhou Road, Nanjing, 210008, China.
Xiaonan LiDepartment of Child Health Care, Children's Hospital of Nanjing Medical University, 72 Guangzhou Road, Nanjing, 210008, China. xiaonan6189@163.com.
Second Affiliated Hospital of Nanjing Medical University · CN

Funding

Jiangsu Province Key Research and Social Development Program BE2015607Natural Science Foundation of China 81773421the Innovation Team of Jiangsu Health CXTDA 2017035
6 · The paper itself

Abstract

backgroundThe aim of this study was to examine the characteristics of diurnal cortisol rhythm in childhood obesity and its relationships with anthropometry, pubertal stage and physical activity.

methodsThirty-five children with obesity (median age: 11.80[interquartile range 10.30, 13.30] and median BMI z-score: 3.21[interquartile range 2.69, 3.71]) and 22 children with normal weight (median age: 10.85[interquartile range 8.98, 12.13] and median BMI z-score: - 0.27[interquartile range - 0.88, 0.35]) were recruited. Saliva samples were collected at 08:00, 16:00 and 23:00 h. Cortisol concentrations at 3 time points, corresponding areas under the curve (AUCs) and diurnal cortisol slope (DCS) were compared between the two groups. Anthropometric measures and pubertal stage were evaluated, and behavioural information was obtained via questionnaires.

resultsChildren with obesity displayed significantly lower cortisol

conclusionsThe disorder of diurnal salivary cortisol rhythm is associated with childhood obesity, which is also influenced by puberty development and physical activity. Thus, stabilizing circadian cortisol rhythms may be an important approach for childhood obesity.

Indexed as

HydrocortisonePediatric ObesityBody Mass IndexChildCircadian RhythmExerciseHumansPubertySalivaHydrocortisoneChildhood obesityCircadian rhythmCortisolPhysical activityPuberty

Identifiers

PMID32782001
PMCPMC7422565
OpenAlexW3048651736

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.