Evidence map›Paper›PMID 32781785›Full record

ArticleBiomolecules2020

Structural Features Mediating Zinc Binding and Transfer in the AztABCD Zinc Transporter System.

Anusha Meni, Erik T Yukl

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Biomolecules, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
0.7field-weighted citation impact, top 31% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 6 citations in OpenAlex.

  1. Structure and Function of the Zinc Binding Protein ZrgA fromInternational journal of molecular sciences · 2022
    Article
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  3. Review
  4. Review
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

Anusha MeniDepartment of Chemistry and Biochemistry, New Mexico State University, Las Cruces, NM 88003, USA.
Erik T YuklDepartment of Chemistry and Biochemistry, New Mexico State University, Las Cruces, NM 88003, USA.ORCID 0000-0001-6519-6938
New Mexico State University · US

Funding

Periplasmic Zinc Management and Homeostasis in Paracoccus denitrificansR01GM122819 · NIGMS · NEW MEXICO STATE UNIVERSITY LAS CRUCES · PI YUKL, ERIK T · 2018 to 2022
$1.4M
Howard Hughes Medical InstituteNIGMS NIH HHS R01 GM122819
6 · The paper itself

Abstract

Many bacteria require ATP binding cassette (ABC) transporters for the import of the essential metal zinc from limited environments. These systems rely on a periplasmic or cell-surface solute binding protein (SBP) to bind zinc with high affinity and specificity. AztABCD is one such zinc transport system recently identified in a large group of diverse bacterial species. In addition to a classical SBP (AztC), the operon also includes a periplasmic metallochaperone (AztD) shown to transfer zinc directly to AztC. Crystal structures of both proteins from

Indexed as

ATP-Binding Cassette TransportersBacterial ProteinsBinding SitesCation Transport ProteinsMolecular Docking SimulationParacoccus denitrificansProtein BindingZincATP-Binding Cassette TransportersBacterial ProteinsCation Transport ProteinsZincABC transporterchaperonemetal homeostasiszinc

Identifiers

PMID32781785
PMCPMC7463823
OpenAlexW3047064778

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.