Evidence map›Paper›PMID 32781670›Full record

ReviewBiomolecules2020

Hormonal Regulation of Mammalian Adult Neurogenesis: A Multifaceted Mechanism.

Claudia Jorgensen, Zuoxin Wang

Abstract readReview
In one paragraph

Review in Biomolecules, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed.

  1. Review
  2. Social Behavior and Neurogenesis.International journal of molecular sciences · 2026
    Review
  3. Review
  4. Observational
  5. Article
  6. Article
  7. Review
  8. Article
  9. Article
  10. Article
  11. Article
  12. Review
  13. Article
  14. Review
  15. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Claudia JorgensenBehavioral Science Department, Utah Valley University, Orem, UT 84058, USA.
Zuoxin WangPsychology Department and Program in Neuroscience, Florida State University, Tallahassee, FL 32306, USA.

Funding

DOPAMINE REGULATION OF SOCIAL ATTACHMENTR01MH058616 · NIMH · FLORIDA STATE UNIVERSITY · PI WANG, ZUOXIN · 2000 to 2016
$3.7M
Epigenetics of social bonding in prairie volesR01MH109450 · NIMH · FLORIDA STATE UNIVERSITY · PI KABBAJ, MOHAMED, WANG, ZUOXIN · 2016 to 2020
$1.9M
Stress, social buffering, and oxytocin regulationR01MH108527 · NIMH · FLORIDA STATE UNIVERSITY · PI WANG, ZUOXIN · 2017 to 2021
$1.9M
NIMH NIH HHS R01 MH058616NIMH NIH HHS R01 MH108527NIMH NIH HHS R01 MH109450
6 · The paper itself

Abstract

Adult neurogenesis-resulting in adult-generated functioning, integrated neurons-is still one of the most captivating research areas of neuroplasticity. The addition of new neurons in adulthood follows a seemingly consistent multi-step process. These neurogenic stages include proliferation, differentiation, migration, maturation/survival, and integration of new neurons into the existing neuronal network. Most studies assessing the impact of exogenous (e.g., restraint stress) or endogenous (e.g., neurotrophins) factors on adult neurogenesis have focused on proliferation, survival, and neuronal differentiation. This review will discuss the multifaceted impact of hormones on these various stages of adult neurogenesis. Specifically, we will review the evidence for hormonal facilitation (via gonadal hormones), inhibition (via glucocorticoids), and neuroprotection (via recruitment of other neurochemicals such as neurotrophin and neuromodulators) on newly adult-generated neurons in the mammalian brain.

Indexed as

NeurogenesisAndrogensAnimalsEstrogensGlucocorticoidsHippocampusHumansNeuronsAndrogensEstrogensGlucocorticoidsadult neurogenesisdentate gyrushippocampushormones

Identifiers

PMID32781670
PMCPMC7465680

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.