Evidence map›Paper›PMID 32781660›Full record

ArticleCells2020

Ruben Esse, Alla Grishok

Open access · goldAbstract read
In one paragraph

Article in Cells, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
0.8field-weighted citation impact, top 33% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 13 citations in OpenAlex.

  1. Article
  2. Article
  3. DOT-1.1 (DOT1L) deficiency inBBA advances · 2023
    Article
  4. Article
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

Ruben EsseDepartment of Biochemistry, BU Genome Science Institute, Boston University School of Medicine, Boston, MA 02118, USA.
Alla GrishokDepartment of Biochemistry, BU Genome Science Institute, Boston University School of Medicine, Boston, MA 02118, USA.
Boston University · US

Funding

Enhancing and expanding the CGC Strain CollectionP40OD010440 · OD · UNIVERSITY OF MINNESOTA · PI Ann E. Rougvie · 2012 to 2026
$7.5M
The role of DOT1L methyltransferase in controlling the noncoding transcriptomeR01GM135199 · NIGMS · BOSTON UNIVERSITY MEDICAL CAMPUS · PI GRISHOK, ALLA · 2020 to 2023
$1.4M
Regulation of RNA processing and transcription by endogenous RNAiR01GM107056 · NIGMS · COLUMBIA UNIVERSITY HEALTH SCIENCES · PI GRISHOK, ALLA · 2014 to 2017
$1.2M
NIGMS NIH HHS R01 GM107056NIGMS NIH HHS R01 GM135199NIH HHS P40 OD010440
6 · The paper itself

Abstract

The methylation of histone H3 at lysine 79 is a feature of open chromatin. It is deposited by the conserved histone methyltransferase DOT1. Recently, DOT1 localization and H3K79 methylation (H3K79me) have been correlated with enhancers in

Indexed as

AnimalsCaenorhabditis elegansCaenorhabditis elegans ProteinsChromatinEnhancer Elements, GeneticHistone-Lysine N-MethyltransferaseHistonesMethylationPromoter Regions, GeneticProtein Processing, Post-TranslationalRNA InterferenceCaenorhabditis elegans ProteinsChromatinDOT-1.1 protein, C elegansHistone-Lysine N-MethyltransferaseHistonesCaenorhabditis elegansChIP-seqchromatinDOT-1.1/DOT1LenhancerH3K79H3K9

Identifiers

PMID32781660
PMCPMC7464606
OpenAlexW3047554603

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.