Evidence map›Paper›PMID 32781567›Full record

ArticlePolymers2020

Poly(ε-caprolactone) Titanium Dioxide and Cefuroxime Antimicrobial Scaffolds for Cultivation of Human Limbal Stem Cells.

Mirna Tominac Trcin, Emilija Zdraveva, Tamara Dolenec, Ivana Vrgoč Zimić, Marina Bujić Mihica, Ivanka Batarilo, Iva Dekaris, Valentina Blažević, Igor Slivac, Tamara Holjevac Grgurić and 8 more

Open access · goldAbstract read
In one paragraph

Article in Polymers, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
1.2field-weighted citation impact, top 18% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 14 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

18 authors at 3 institutions in 1 country.

Mirna Tominac TrcinThe Institute of Immunology, Rockefellerova ul. 2, 10000 Zagreb, Croatia.
Emilija ZdravevaFaculty of Textile Technology, University of Zagreb, Prilaz baruna Filipovića 28a, 10000 Zagreb, Croatia.
Tamara DolenecDepartment of Transfusion and Regenerative Medicine, Sestre Milosrdnice University Hospital Center, Draškovićeva 19, 10000 Zagreb, Croatia.
Ivana Vrgoč ZimićDepartment of Transfusion and Regenerative Medicine, Sestre Milosrdnice University Hospital Center, Draškovićeva 19, 10000 Zagreb, Croatia.
Marina Bujić MihicaDepartment of Transfusion and Regenerative Medicine, Sestre Milosrdnice University Hospital Center, Draškovićeva 19, 10000 Zagreb, Croatia.
Ivanka BatariloDepartment of Microbiology, Croatian Institute for Transfusion Medicine, Petrova 3, 10000 Zagreb, Croatia.
Iva DekarisMedical Faculty of Rijeka, University Eye Hospital Svjetlost, Vjekoslava Heinzela 39, 10000 Zagreb, Croatia.
Valentina BlaževićSchool of Medicine, University of Zagreb, Šalata 2, 10000 Zagreb, Croatia.
Igor SlivacFaculty of Food Technology and Biotechnology, University of Zagreb, Pierottijeva 6, 10000 Zagreb, Croatia.
Tamara Holjevac GrgurićFaculty of Metallurgy, University of Zagreb, Aleja narodnih heroja 3, 44000 Sisak, Croatia.ORCID 0000-0002-2973-2200
Emi Govorčin BajsićFaculty of Chemical Engineering and Technology, University of Zagreb, Marulićev trg 19, 10000 Zagreb, Croatia.
Ksenija MarkovFaculty of Food Technology and Biotechnology, University of Zagreb, Pierottijeva 6, 10000 Zagreb, Croatia.
Iva ČanakFaculty of Food Technology and Biotechnology, University of Zagreb, Pierottijeva 6, 10000 Zagreb, Croatia.ORCID 0000-0003-0973-138X
Sunčica KuzmićForensic Science Centre, Ivan Vučetić", Ilica 335, 10000 Zagreb, Croatia.
Anita TarbukFaculty of Textile Technology, University of Zagreb, Prilaz baruna Filipovića 28a, 10000 Zagreb, Croatia.ORCID 0000-0002-4539-2103
Antoneta TomljenovićFaculty of Textile Technology, University of Zagreb, Prilaz baruna Filipovića 28a, 10000 Zagreb, Croatia.
Nikolina MrkonjićFaculty of Chemical Engineering and Technology, University of Zagreb, Marulićev trg 19, 10000 Zagreb, Croatia.
Budimir MijovićFaculty of Textile Technology, University of Zagreb, Prilaz baruna Filipovića 28a, 10000 Zagreb, Croatia.
University of Zagreb · HRCroatian Institute of Transfusion Medicine · HRInstitute of Immunology · HR

Funding

Hrvatska Zaklada za Znanost 6878
6 · The paper itself

Abstract

Limbal Stem Cell Deficiency (LSCD) is a very serious and painful disease that often results in impaired vision. Cultivation of limbal stem cells for clinical application is usually performed on carriers such as amniotic membrane or surgical fibrin gel. Transplantation of these grafts is associated with the risk of local postoperative infection that can destroy the graft and devoid therapeutic benefit. For this reason, electrospun scaffolds are good alternatives, as proven to mimic the natural cells surroundings, while their fabrication technique is versatile with regard to polymer functionalization and scaffolds architecture. This study considers the development of poly(ε-caprolactone) (PCL) immune-compatible and biodegradable electrospun scaffolds, comprising cefuroxime (CF) or titanium dioxide (TiO

Indexed as

antimicrobial activitycefuroximeelectrospinninglimbal stem cell deficiencypolycaprolactonescaffoldstissue engineeringtitanium dioxide

Identifiers

PMID32781567
PMCPMC7465675
OpenAlexW3047098437

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.