ArticleArchives of gerontology and geriatrics
The Mexican Cognitive Aging Ancillary Study (Mex-Cog): Study Design and Methods.
Article in Archives of gerontology and geriatrics. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 42 papers.
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Who cites it
42 citing papers in PubMed.
- Cohort Profile Update: cognition and ageing in the Survey of Health, Ageing and Retirement in Europe Harmonized Cognitive Assessment Protocol (SHARE-HCAP).International journal of epidemiology · 2026Article
- Low-burden AI approach for cross-national early identification of cognitive impairment using real-world questionnaire response behaviours.Nature communications · 2026Article
- Methodological adaptations for applying the Harmonised Cognitive Assessment Protocol diagnostic algorithm in the Northern Ireland Cohort for the Longitudinal Study of Ageing (NICOLA-HCAP).BMC research notes · 2026Article
- A study evaluation framework for measuring cognition: lessons learned in cross-national contexts from four English-speaking aging cohorts.European journal of epidemiology · 2026Article
- Numeracy, literacy, and formal education as mechanisms of inequities in late-life cognitive performance between Indigenous-speaking and non-Indigenous-speaking older Mexican adults.Alzheimer's & dementia : the journal of the Alzheimer's Association · 2026Article
- Cohort Profile Update: The Harmonised Cognitive Assessment Protocol sub-study of the Northern Ireland Cohort for the Longitudinal Study of Ageing (NICOLA-HCAP).International journal of epidemiology · 2026Article
- Prevalence of dementia and mild cognitive impairment in the Mexican population: evidence from Mex-Cog, a harmonized cognitive assessment protocol study.The journals of gerontology. Series B, Psychological sciences and social sciences · 2026Article
- Recommended best practices for construct-centered adaptation of the Harmonized Cognitive Assessment Protocol.The journals of gerontology. Series B, Psychological sciences and social sciences · 2026Article
- The measurement of cognition in large-scale cross-national surveys: lessons from the Health and Retirement Study International Network of Studies and the Harmonized Cognitive Assessment Protocol.The journals of gerontology. Series B, Psychological sciences and social sciences · 2026Article
- Harmonized Cognitive Assessment Protocol: What makes an HCAP an HCAP? An adaptive architecture for measuring cognitive aging around the world.The journals of gerontology. Series B, Psychological sciences and social sciences · 2026Article
- Article
- Validation of cognitive and psychosocial tools in Kenya: findings from the LOSHAK feasibility pilot.BMC public health · 2025Article
- Estimating cognitive decline in longitudinal studies with high mortality and a long interwave period: A comparison of approaches and considerations around integrating end-of-life interview data.Alzheimer's & dementia : the journal of the Alzheimer's Association · 2025Article
- Visual Scanning and Falls in Older Adults: The Mexico Health and Aging Study.Journal of the American Geriatrics Society · 2025Article
- Own and parental schooling, gender, and cognitive performance based on the Harmonized Cognitive Assessment Protocol (HCAP) among older Chilean adults.The journals of gerontology. Series B, Psychological sciences and social sciences · 2025Article
- The predictive power of employment trajectories on cognition of older adults: Evidence from Chile.Social science & medicine (1982) · 2025Article
- The Caribbean American Dementia and Aging Study: protocol for a population-based study of older adult health and dementia in Cuba, the Dominican Republic, and Puerto Rico.BMC geriatrics · 2025Article
- Midlife cognitive testing in Africa: validity of the Harmonised Cognitive Assessment Protocol in the Kenya Life Panel Survey.BMJ open · 2025Article
- Validation of harmonized cognitive assessment protocol within the Egyptian context.Social psychiatry and psychiatric epidemiology · 2025Article
- APOE and Alzheimer's disease and related dementias risk among 12,221 Hispanics/Latinos.Alzheimer's & dementia : the journal of the Alzheimer's Association · 2025Article
Corrections and comments
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Authors and funding
8 authors.
Funding
Abstract
objectiveDescribe the protocol sample and instruments of the Cognitive Aging Ancillary Study in Mexico (Mex-Cog). The study performs an in-depth cognitive assessment in a subsample of older adults of the ongoing Mexican Health and Aging Study (MHAS). The Mex-Cog is part of the Harmonized Cognitive Assessment Protocol (HCAP) design to facilitate cross-national comparisons of the prevalence and trends of dementia in aging populations around the world, funded by the National Institute on Aging (NIA).
methodsThe study protocol consists of a cognitive assessment instrument for the target subject and an informant questionnaire. All cognitive measures were selected and adapted by a team of experts from different ongoing studies following criteria to warrant reliable and comparable cognitive instruments. The informant questionnaire is from the 10/66 Dementia Study in Mexico.
resultsA total of 2,265 subjects aged 55-104 years participated, representing a 70% response rate. Validity analyses showed the adequacy of the content validity, proper quality-control procedures that sustained data integrity, high reliability, and internal structure.
conclusionsThe Mex-Cog study provides in-depth cognitive data that enhances the study of cognitive aging in two ways. First, linking to MHAS longitudinal data on cognition, health, genetics, biomarkers, economic resources, health care, family arrangements, and psychosocial factors expands the scope of information on cognitive impairment and dementia among Mexican adults. Second, harmonization with other similar studies around the globe promotes cross-national studies on cognition with comparable data. Mex-Cog data is publicly available at no cost to researchers.
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