Evidence map›Paper›PMID 32781042›Full record

ArticleCancer cell2020

Neutrophil DNA Webs Untangled.

Simon Milette, Daniela F Quail, Jonathan D Spicer

Abstract readComment
PubMed Publisher
In one paragraph

Article in Cancer cell, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Article
  3. Article
  4. Review
  5. Review
  6. Article
  7. Review
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

3 authors.

Simon MiletteDepartment of Medicine, Division of Experimental Medicine, McGill University, Montreal, Canada; Rosalind and Morris Goodman Cancer Research Centre, McGill University, Montreal, Canada; Cancer Research Program, Research Institute of the McGill University Health Centre, Montreal, Canada.
Daniela F QuailDepartment of Medicine, Division of Experimental Medicine, McGill University, Montreal, Canada; Rosalind and Morris Goodman Cancer Research Centre, McGill University, Montreal, Canada; Department of Physiology, Faculty of Medicine, McGill University, Montreal, Canada. Electronic address: daniela.quail@mcgill.ca.
Jonathan D SpicerDepartment of Medicine, Division of Experimental Medicine, McGill University, Montreal, Canada; Rosalind and Morris Goodman Cancer Research Centre, McGill University, Montreal, Canada; Cancer Research Program, Research Institute of the McGill University Health Centre, Montreal, Canada; Department of Surgery, Faculty of Medicine, McGill University, Montreal, Canada. Electronic address: jonathan.spicer@mcgill.ca.

Funding

CIHR
6 · The paper itself

Abstract

Neutrophil extracellular traps (NETs) have been implicated in a wide array of biological processes extending beyond the containment of infection, including metastatic dissemination. A recent publication in Nature highlights a NETs-dependent mechanism that directly enhances the invasive and proliferative properties of cancer cells.

Indexed as

Extracellular TrapsNeutrophilsDNADNA

Identifiers

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.