ArticleEpilepsia2020
Temporal lobe regions essential for preserved picture naming after left temporal epilepsy surgery.
Article in Epilepsia, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 39 papers, 2 of them syntheses that pooled it.
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Who cites it
39 citing papers in PubMed, 2 syntheses or guidelines pooled it.
- Clinical and anatomical characteristics of basal temporal seizures: A systematic review.Epileptic disorders : international epilepsy journal with videotape · 2025Pooled it
- Roles of fMRI and Wada tests in the presurgical evaluation of language functions in temporal lobe epilepsy.Frontiers in neurology · 2022Pooled it
- Article
- Beyond Broca and Wernicke: Epilepsy surgery in the language areas.Epileptic disorders : international epilepsy journal with videotape · 2026Review
- Contralateral language network integration predicts and protects against naming decline after temporal lobe resection.Epilepsia · 2026Article
- Cognitive safety under epicranial cortex stimulation of the epileptic focus.Epilepsia open · 2026Observational
- Telehealth enabled neuropsychological testing (TENT): a new platform for examiner-led, digital cognitive assessment.Journal of neurology · 2026Article
- Medial Pulvinar Nucleus as a Causal Hub for Heteromodal Naming.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2026Article
- Frontotemporal network interactions causally support rapid concreteness judgments during reading.PLoS biology · 2026Article
- Article
- Object naming after epilepsy surgery in the dominant left temporal lobe: risk factors, time course and long-term outcome.Journal of neurology, neurosurgery, and psychiatry · 2025Article
- Lesion and lesion network localization of dysnomia after epilepsy surgery.Brain : a journal of neurology · 2025Article
- Networks for proper versus common name retrieval: insights from causal mapping and new hypotheses.Brain communications · 2025Review
- Impact of anterior callosal disconnection on picture naming in frontal lobe epilepsy surgery.Brain communications · 2025Article
- Consensus recommendations for clinical functional MRI applied to language mapping.Aperture neuro · 2025Article
- A Rose by Any Other Name: Mapping Taxonomic and Thematic Naming Errors Poststroke.Journal of cognitive neuroscience · 2024Article
- Dissociation of reading and naming in ventral occipitotemporal cortex.Brain : a journal of neurology · 2024Article
- Naming fMRI-guided white matter language tract volumes influence naming decline after temporal lobe resection.Journal of neurology · 2024Article
- Stimulation of caudal inferior and middle frontal gyri disrupts planning during spoken interaction.Current biology : CB · 2024Article
- An inclusive multivariate approach to neural localization of language components.Brain structure & function · 2024Article
Corrections and comments
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Authors and funding
27 authors.
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Abstract
objectiveTo define left temporal lobe regions where surgical resection produces a persistent postoperative decline in naming visual objects.
methodsPre- and postoperative brain magnetic resonance imaging data and picture naming (Boston Naming Test) scores were obtained prospectively from 59 people with drug-resistant left temporal lobe epilepsy. All patients had left hemisphere language dominance at baseline and underwent surgical resection or ablation in the left temporal lobe. Postoperative naming assessment occurred approximately 7 months after surgery. Surgical lesions were mapped to a standard template, and the relationship between presence or absence of a lesion and the degree of naming decline was tested at each template voxel while controlling for effects of overall lesion size.
resultsPatients declined by an average of 15% in their naming score, with wide variation across individuals. Decline was significantly related to damage in a cluster of voxels in the ventral temporal lobe, located mainly in the fusiform gyrus approximately 4-6 cm posterior to the temporal tip. Extent of damage to this region explained roughly 50% of the variance in outcome. Picture naming decline was not related to hippocampal or temporal pole damage. SIGNIFICANCE: The results provide the first statistical map relating lesion location in left temporal lobe epilepsy surgery to picture naming decline, and they support previous observations of transient naming deficits from electrical stimulation in the basal temporal cortex. The critical lesion is relatively posterior and could be avoided in many patients undergoing left temporal lobe surgery for intractable epilepsy.
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